Observational studyScientific reports2025
Troponin, NT-proBNP and postoperative atrial fibrillation in a prospective cohort undergoing coronary artery bypass surgery.
Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
Troponin and N-terminal pro B-type natriuretic peptide (NT-proBNP) are biomarkers of cardiac damage and myocyte stretch. The existing evidence on the predictive value of preoperative high-sensitive Troponin and NT-proBNP concentration for the onset of postoperative atrial fibrillation (POAF) is inconsistent. Therefore, we aimed to assess these biomarkers as predictors for POAF in a prospective observational cohort study of patients without atrial fibrillation undergoing coronary artery bypass graft surgery (CABG). We analysed 423 patients with a median age of 66.3 years, 15.1% were women. About a third of these patients (N = 135, 32.4%) developed POAF. The median concentration of (25th, 75th percentile) high-sensitive Troponin at baseline was 11.8 (5.6, 42.7) ng/l in the POAF group and 11.4 (5.2, 37.0) ng/l in the group without POAF, median NT-proBNP was 255 (131, 621) ng/l in the POAF group and 184 (91, 497) in the group without POAF. In uni- and multivariable analyses neither biomarker showed statistically significant associations with POAF. These findings add further neutral data to the inconsistent results found in the current literature and mandate the search for better clinical or biomarker information to assess the risk of this common complication of CABG surgery.
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