Evidence map›Paper›PMID 40775391›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Surgeon-performed point-of-care ultrasound and ultrasound-guided core biopsy reduce diagnostic invasiveness in primary thyroid lymphoma.

Chun-Nan Chen, Tai-Chung Huang, Yu-Hsuan Tuan, Shan-Chi Yu, Shyang-Rong Shih, Tsung-Lin Yang

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Chun-Nan Chen *Department of Otolaryngology, National Taiwan University Hospital, National Taiwan University College of Medicine, #1, Sec. 1 Jen-Ai Road, Taipei, 100, Taiwan.
Tai-Chung Huang *Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Yu-Hsuan TuanDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Shan-Chi YuDepartment of Pathology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Shyang-Rong ShihDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Tsung-Lin YangDepartment of Otolaryngology, National Taiwan University Hospital, National Taiwan University College of Medicine, #1, Sec. 1 Jen-Ai Road, Taipei, 100, Taiwan. yangtl@ntu.edu.tw.ORCID http://orcid.org/0000-0001-6521-8631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePrimary thyroid lymphoma (PTL) is a rare thyroid malignancy, with chemotherapy with/without radiation therapy being the primary treatments. Surgery is typically reserved for diagnostic purposes and unnecessary surgeries increased risk of operation and post-operative hypothyroidism. A minimally invasive diagnostic approach is essential for PTL to minimize potential complications.

methodsA retrospective review for patients diagnosed with PTL at a tertiary medical center between 2007 and 2024 was conducted. The data on demographics, diagnostic procedures, cytopathological results, costs, procedure times, and post-procedure complications were collected for analysis.

resultsDiagnostic methods among 25 pathologically confirmed PTL included ultrasound-guided core biopsy (USCB) for 10 patients, open biopsy for 4, unilateral thyroid lobectomy for 6, and total thyroidectomy for 5. The lymphoma subtypes included 13 patients with diffuse large B-cell lymphoma, 1 with follicular lymphoma, and 11 with mucosa-associated lymphoid tissue lymphoma. The USCB group had the lowest incidence of post-treatment hypothyroidism, lower cost, shorter procedure time, and smaller wound size.

conclusionSurgeon-performed ultrasound and USCB offers a minimally invasive, cost-effective and timely approach for diagnosing primary thyroid lymphoma, with better functional preservation.

Indexed as

Image-Guided BiopsyLymphomaPoint-of-Care SystemsThyroid NeoplasmsUltrasonography, InterventionalAdultAgedBiopsy, Large-Core NeedleFemaleHumansMaleMiddle AgedNeoplasm InvasivenessRetrospective StudiesThyroidectomyMinimally-invasive approachOpen biopsyPrimary thyroid lymphomaThyroidectomyUltrasound-guided core biopsy

Identifiers

PMID40775391

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