ArticleBMC oral health2025
Comparative evaluation of 38% silver diamine fluoride on sealing ability of biodentine and MTA angelus as a perforation repair material: a confocal laser microscopic study.
Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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5 authors.
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Abstract
backgroundThe objective of this research was to evaluate and compare the effect of 38% Silver Diamine Fluoride(SDF) on the sealing ability of Biodentine (BD) and MTA (Mineral Trioxide Aggregate) Angelus when utilized as a perforation repair material for human-extracted mandibular molars. MATERIALS AND
methodsForty human mandibular molars were extracted and divided into four groups (N = 10): Group 1 (BD), Group 2 (BD + SDF), Group 3 (MTA), and Group 4 (MTA + SDF). Standardized access cavities were prepared, and a 2 mm perforation was created at the pulpal floor. In Groups 2 and 4, SDF was applied for three minutes, followed by rinsing and air drying before placing BD or MTA. The restorations were then left to set for 48 h under humid conditions. Afterward, the specimens were immersed in a 0.6% rhodamine B dye solution for another 48 h. Each tooth was sectioned longitudinally, and dye penetration along the interface was examined under a confocal laser microscope at 40X magnification. Statistical analysis was performed using SPSS software, with one-way ANOVA and post hoc Tukey tests applied to determine significance (p < 0.05).
resultsThe intergroup analysis showed significant differences in dye penetration (p < 0.01). Group 3 (MTA) exhibited the least dye penetration followed by Group 2 (BD + SDF) and Group 4 (MTA + SDF). Group 1 (BD) demonstrated the highest dye penetration indicating the weakest sealing ability. The post hoc Tukey test confirmed that Group 1 had significantly higher microleakage than Groups 2, 3, and 4 (p < 0.001). While SDF significantly improved BD's sealing ability (Group 2 vs. Group 1, p < 0.001), its effect on MTA was not statistically significant (Group 4 vs. Group 3, p = 0.530).
conclusionMTA and BD, the primary materials used for perforation repair, face challenges related to solubility. Since SDF is nearly insoluble, it has the potential to form a protective barrier, enhancing marginal sealing and minimizing microleakage. However, there is currently no research examining how SDF influences the microleakage of MTA and BD in perforation repair. This in vitro study seeks to assess the impact of SDF on the sealing properties of these calcium silicate-based materials, providing valuable insights into improving perforation repair techniques.
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