SynthesisBMC pediatrics2025
Risk factors for allergic rhinitis in preschool children: a meta-analysis and systematic review.
Synthesis in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors for allergic rhinitis in children: an umbrella review of systematic review and meta-analysis.Frontiers in immunology · 2026Pooled it
- Mechanism of RNA-Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis.The Kaohsiung journal of medical sciences · 2026Article
- Prediction of future onset of allergic rhinitis and analysis of risk factors in children with food allergy during infancy.European journal of pediatrics · 2026Article
- The Burden of Early-Childhood Atopic Disease: Prevalence and Risk Factors for Allergic Rhinitis in an Informal Settlement in South Africa.Children (Basel, Switzerland) · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundAllergic rhinitis (AR) is a common disease in preschool children and seriously affects their quality of life. Defining the risk factors of AR can help early diagnosis and prevention. The aim of this meta-analysis was to identify and summarizes the risk factors associated with allergic rhinitis in preschool children.
methodsA systematic search of PubMed, Embase, Cochrane library, Web of Science, built up to 20 January 2025 was performed. Studies were included if they reported risk factors for AR in preschool children. A random-effects model was used to calculate the combined odd ratio (OR) and 95% confidence interval (CI).
resultsA total of 10 cohort studies involving 94,774 preschool children were included in this meta-analysis. The results suggested that several factors may associated with higher odds of allergic rhinitis in preschool children. These factors include parental allergic rhinitis (OR = 2.4, 95% CI: 2.01-2.87), parental eczema (OR = 1.72, 95% CI: 1.48-1.99), parental asthma (OR = 2.45, 95% CI: 1.53-3.93), male (OR = 1.54, 95% CI: 1.37-1.72), caesarean birth (OR = 1.32, 95% CI: 1.08-1.61), and dampness at home (OR = 1.24, 95% CI: 1.08-1.42). On the other hand, the presence of pets at home was found to be protective, with a reduced risk of allergic rhinitis (OR = 0.57, 95% CI: 0.41-0.78).
conclusionThis study suggests that factors such as parental history of allergy, boys, caesarean section and damp environment at home may increase the risk of allergic rhinitis in preschool children, whereas pets may have a protective role. These findings emphasize the influence of genetic and environmental factors on allergic rhinitis in children.
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