Evidence map›Paper›PMID 40775304›Full record

ArticleBMC psychiatry2025

Trauma and ICD-11 PTSD in substance use disorder treatment: a Danish multi-site study.

S Karsberg, L Najavits, M U Pedersen, A Elklit, M L Vang

Abstract readMulticenter Study
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

S KarsbergCentre for Alcohol and Drug Research, Department of Psychology, Aarhus University, Aarhus, Denmark. sk.crf@psy.au.dk.
L NajavitsUniversity of Massachusetts Chan Medical School, Worcester, MA, USA.
M U PedersenUniversity of Massachusetts Chan Medical School, Worcester, MA, USA.
A ElklitDanish Center of Psychotraumatology, Unit of Clinical Psychology and Existence, Relation and Society, Department of Psychology, University of Southern Denmark, Odense, Denmark.
M L VangDanish Center of Psychotraumatology, Unit of Clinical Psychology and Existence, Relation and Society, Department of Psychology, University of Southern Denmark, Odense, Denmark.

Funding

TrygFonden 154804
6 · The paper itself

Abstract

backgroundPrevious research has indicated high levels of PTSD among people with substance use disorder (SUD). This study expands that work to a Danish SUD population, assessing the prevalence of ICD-11 PTSD diagnoses, sociodemographics, and trauma- and substance-related factors. We also compare differences between individuals in treatment for alcohol use disorder (AUD) and drug use disorder (DUD).

methodsThe study used a multi-site approach, with data from five Danish SUD treatment settings. A total of 1347 adults were interviewed as part of an initial structured screening for SUD treatment. Participants were assessed using ICD-11 PTSD criteria.

resultsApproximately 25% of individuals in treatment met criteria for probable PTSD, with an additional 15% evidencing subclinical PTSD. PTSD prevalence was higher in DUD treatment than AUD treatment. The study also highlights significant differences in social functioning and clinical profiles between the two groups.

conclusionThe high prevalence of PTSD symptoms among individuals in SUD treatment indicates a need for targeted interventions. PTSD should be a particular focus in DUD treatment due to the high vulnerability and prevalence of trauma-related symptoms in this subgroup.

Indexed as

Stress Disorders, Post-TraumaticSubstance-Related DisordersAdultComorbidityDenmarkFemaleHumansInternational Classification of DiseasesMaleMiddle AgedPrevalenceYoung AdultPTSDSubstance use disorderTherapyTrauma

Identifiers

PMID40775304
PMCPMC12330125

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.