ArticleCommunications medicine2025
A cross-national analysis of childhood predictors of physical pain.
Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- The association between age at menarche and subsequent risk of chronic pain.Frontiers in global women's health · 2026Review
- A comparative "report card" wellbeing assessment of 22 countries in the Global Flourishing Study.Discover global society · 2026Article
- Are the Previously Reported Risk Factors for Endometriosis Actually Associated With Pain and Infertility Rather Than Endometriosis Itself?Reproductive medicine and biologyReview
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe socioeconomic, psychosocial, and behavioural factors that influence physical pain have been largely explored. However, evidence on the childhood circumstances that shape physical pain in adulthood is scarce.
methodsUsing a nationally representative dataset of 202,898 individuals (Age range: 18-99, 49% female, 51% male, 0.03% other) from 22 countries and a random effects meta-analysis, we examine 13 potential childhood predictors of physical pain in adulthood.
resultsWe find that childhood experiences, personal attributes, and familial and social circumstances have meaningful and varied associations with adulthood levels of physical pain. Specifically, we find that people whose parents were divorced, single, or died (vs married) when they were children, those who reported that their family found it very difficult to live with their family's household income when they were growing up (vs got by), those who experienced abuse (vs not), felt like an outsider (vs not), reported poor physical health while growing up (vs good) and reported more frequent religious attendance at age 12 (vs never) have a greater risk of experiencing pain later in life. The strength of these associations differs by country reflecting diverse societal influences.
conclusionsOur study provides valuable insights on the early-life experiences that shape physical pain in adulthood. These findings enhance our understanding of early-life predictors of adult wellbeing and offer comprehensive evidence for designing interventions to reduce physical pain levels.
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Registered trials
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