Evidence map›Paper›PMID 40775017›Full record

ArticleCommunications medicine2025

A cross-national analysis of childhood predictors of physical pain.

Lucía Macchia, Chukwuemeka N Okafor, Thomas Breedlove, Koichiro Shiba, Alan Piper, Byron Johnson, Tyler J VanderWeele

Abstract read
In one paragraph

Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucía MacchiaSchool of Health and Medical Sciences, City St George's, University of London, London, UK. lucia.macchia@citystgeorges.ac.uk.ORCID http://orcid.org/0000-0001-9558-4747
Chukwuemeka N OkaforLong School of Medicine, University of Texas Health Science Center San Antonio, San Antonio, USA, TX.ORCID http://orcid.org/0000-0002-6080-4866
Thomas BreedloveInstitute for Studies of Religion, Baylor University, Waco, TX, USA.
Koichiro ShibaBoston University School of Public Health, Boston, MA, USA.
Alan PiperLeeds University Business School, Leeds, UK.
Byron JohnsonInstitute for Studies of Religion, Baylor University, Waco, TX, USA.
Tyler J VanderWeeleHuman Flourishing Program, Harvard University, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-6112-0239

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe socioeconomic, psychosocial, and behavioural factors that influence physical pain have been largely explored. However, evidence on the childhood circumstances that shape physical pain in adulthood is scarce.

methodsUsing a nationally representative dataset of 202,898 individuals (Age range: 18-99, 49% female, 51% male, 0.03% other) from 22 countries and a random effects meta-analysis, we examine 13 potential childhood predictors of physical pain in adulthood.

resultsWe find that childhood experiences, personal attributes, and familial and social circumstances have meaningful and varied associations with adulthood levels of physical pain. Specifically, we find that people whose parents were divorced, single, or died (vs married) when they were children, those who reported that their family found it very difficult to live with their family's household income when they were growing up (vs got by), those who experienced abuse (vs not), felt like an outsider (vs not), reported poor physical health while growing up (vs good) and reported more frequent religious attendance at age 12 (vs never) have a greater risk of experiencing pain later in life. The strength of these associations differs by country reflecting diverse societal influences.

conclusionsOur study provides valuable insights on the early-life experiences that shape physical pain in adulthood. These findings enhance our understanding of early-life predictors of adult wellbeing and offer comprehensive evidence for designing interventions to reduce physical pain levels.

Identifiers

PMID40775017
PMCPMC12331892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.