Evidence map›Paper›PMID 40774988›Full record

ReviewNPJ microgravity2025

Blood flow restriction training in microgravity: a review of multisystem physiological benefits and implementation challenges for long-duration space missions.

Mingzhen Hu, Wei Li, Qiushi Yin, Yuqing Liu, Lin Chen, Qin Ru, Guodong Xu, Yuxiang Wu

Abstract readReview
In one paragraph

Review in NPJ microgravity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mingzhen Hu *College of Sports Medicine, Wuhan Sports University, Wuhan, China.
Wei Li *College of Sports Medicine, Wuhan Sports University, Wuhan, China.
Qiushi YinCollege of Sports Medicine, Wuhan Sports University, Wuhan, China.
Yuqing LiuCollege of Sports Medicine, Wuhan Sports University, Wuhan, China.
Lin ChenInstitute of Intelligent Sport and Proactive Health, Department of Health and Physical Education, Jianghan University, Wuhan, China.
Qin RuInstitute of Intelligent Sport and Proactive Health, Department of Health and Physical Education, Jianghan University, Wuhan, China.
Guodong XuInstitute of Intelligent Sport and Proactive Health, Department of Health and Physical Education, Jianghan University, Wuhan, China.
Yuxiang WuCollege of Sports Medicine, Wuhan Sports University, Wuhan, China. yxwu@jhun.edu.cn.

Funding

National Natural Science Foundation of China 82071970National Natural Science Foundation of China 82272123Science and Technology Project of Jianghan University 2022XKZX008Science Fund for Distinguished Young Scholars of Hubei Province 2023AFA109
6 · The paper itself

Abstract

This review evaluates BFRT as a novel countermeasure against multisystem deconditioning (muscle atrophy, bone loss, cardiovascular impairment) during long-duration space missions. BFRT combines low-load exercise with vascular occlusion, mimicking high-intensity benefits while reducing equipment needs. We synthesize evidence for BFRT's efficacy in microgravity analogs, discusses implementation challenges (equipment adaptation, safety protocols, sex-specific responses), and highlight its potential as a space-efficient adjunct to current exercise regimens, informing future mission planning.

Identifiers

PMID40774988
PMCPMC12332010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.