Evidence map›Paper›PMID 40774953›Full record

ArticleNature communications2025

Artificial transneurons emulate neuronal activity in different areas of brain cortex.

Rivu Midya, Ambarish S Pawar, Debi P Pattnaik, Eric Mooshagian, Pavel Borisov, Thomas D Albright, Lawrence H Snyder, R Stanley Williams, J Joshua Yang, Alexander G Balanov and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rivu Midya *Department of Electrical and Computer Engineering, University of Massachusetts, Amherst, MA, USA.
Ambarish S Pawar *Systems Neurobiology Laboratories, Salk Institute for Biological Studies, La Jolla, CA, USA.
Debi P Pattnaik *Department of Physics, Loughborough University, Loughborough, UK.ORCID http://orcid.org/0009-0008-9262-174X
Eric Mooshagian *Department of Cognitive Science, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-5998-8445
Pavel BorisovDepartment of Physics, Loughborough University, Loughborough, UK.ORCID http://orcid.org/0000-0003-1464-6999
Thomas D AlbrightSystems Neurobiology Laboratories, Salk Institute for Biological Studies, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-0691-5992
Lawrence H SnyderDepartment of Neuroscience, Washington University School of Medicine, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-3776-0199
R Stanley WilliamsDepartment of Electrical and Computer Engineering, Texas A&M University, College Station, TX, USA.ORCID http://orcid.org/0000-0003-0213-4259
J Joshua YangDepartment of Electrical and Computer Engineering, University of Massachusetts, Amherst, MA, USA. jjoshuay@usc.edu.ORCID http://orcid.org/0000-0001-8242-7531
Alexander G BalanovDepartment of Physics, Loughborough University, Loughborough, UK. a.balanov@lboro.ac.uk.ORCID http://orcid.org/0000-0002-1678-0756
Sergei GepshteinSystems Neurobiology Laboratories, Salk Institute for Biological Studies, La Jolla, CA, USA. sergei@salk.edu.ORCID http://orcid.org/0000-0002-6328-7972
Sergey E Savel'evDepartment of Physics, Loughborough University, Loughborough, UK. s.saveliev@lboro.ac.uk.ORCID http://orcid.org/0000-0003-2771-230X

Funding

VISUAL-MOTOR TRANSFORMATIONS IN PARIETAL CORTEXR01EY012135 · NEI · WASHINGTON UNIVERSITY · PI SNYDER, LAWRENCE H · 2000 to 2023
$8.4M
Core Grant for Vision ResearchP30EY019005 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ALBRIGHT, THOMAS D · 2009 to 2018
$7.7M
Neural mechanisms of visual sensitivityR01EY029117 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ALBRIGHT, THOMAS D, GEPSHTEIN, SERGEI · 2019 to 2023
$2.4M
Neural basis of limb selection in unimanual reachingR01NS123435 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ERIC F MOOSHAGIAN · 2022 to 2026
$2.2M
Neural mechanisms underlying adaptive optimization of visual sensitivityR01EY018613 · NEI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ALBRIGHT, THOMAS D, GEPSHTEIN, SERGEI · 2011 to 2013
$1.5M
Efficient resource allocation and information retention in working memory circuitsR01EB028154 · NIBIB · WASHINGTON UNIVERSITY · PI CHING, SHINUNG, SNYDER, LAWRENCE H · 2019 to 2019
$1.1M
NEI NIH HHS P30 EY019005NEI NIH HHS R01 EY012135NEI NIH HHS R01 EY018613NEI NIH HHS R01 EY029117NIBIB NIH HHS R01 EB028154NINDS NIH HHS R01 NS123435RCUK | Engineering and Physical Sciences Research Council (EPSRC) EP/S032843/1United States Department of Defense | United States Air Force | AFMC | Air Force Office of Scientific Research (AF Office of Scientific Research) FA9550-19-1-0213U.S. Department of Health & Human Services | NIH | National Eye Institute (NEI) R01 EY018613; P30 EY019005U.S. Department of Health & Human Services | NIH | National Eye Institute (NEI) R01-EY029117U.S. Department of Health & Human Services | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) 1R01EB028154
6 · The paper itself

Abstract

Rapid development of memristive elements emulating biological neurons creates new opportunities for brain-like computation at low energy consumption. A first step toward mimicking complex neural computations is the analysis of single neurons and their characteristics. Here we measure and model spiking activity in artificial neurons built using diffusive memristors. We compare activity of these artificial neurons with the spiking activity of biological neurons measured in sensory, pre-motor, and motor cortical areas of the monkey (male) brain. We find that artificial neurons can operate in diverse self-sustained and noise-induced spiking regimes that correspond to the activity of different types of cortical neurons with distinct functions. We demonstrate that artificial neurons can function as trans-functional devices (transneurons) that reconfigure their behaviour to attain instantaneous computational needs, each capable of emulating several biological neurons.

Indexed as

Cerebral CortexModels, NeurologicalNeuronsAction PotentialsAnimalsMacaca mulattaMaleMotor Cortex

Identifiers

PMID40774953
PMCPMC12332047

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.