ArticleBiosensors & bioelectronics2025
Rapid simultaneous self-testing of HIV and HCV viral loads with integrated RNA extraction and multiplex RT-PCR in under 1 hour.
Article in Biosensors & bioelectronics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Immunomagnetic Sample Preparation Targeting Host- and Viral-Derived Antigens for HIV-1 Isolation from Limited Plasma Volumes.Analytical chemistry · 2026Article
- ViraLite: An Ultracompact HIV Viral Load Self-Testing System with Internal Quality Control.medRxiv : the preprint server for health sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
HIV and HCV Co-infection continues to be a significant public health problem globally especially within high-risk groups. Monitoring viral loads with precision helps direct treatment choices and measure treatment success while preventing resistance to drugs. Traditional laboratory-based testing faces limitations due to restricted accessibility and dependence on centralized facilities along with the complex process of quantifying both HIV and HCV viral loads which impedes worldwide control measures for these viruses. We developed a portable self-testing device that measures HIV and HCV viral loads from a 100 μL finger-prick blood sample at the same time. The system combines RNA extraction with rapid multiplex RT-PCR to provide semi-automated testing capabilities and generate results in under 1 h. The system extracts RNA at 80 % efficiency and employs a three-channel optical detection system that detects as low as 5 copies per reaction while delivering high sensitivity and accuracy. Validated studies found a robust connection with Bio-Rad benchtop systems (R
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Registered trials
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