ArticleJournal of microbiology and biotechnology2025
Polystyrene Accelerates Aging Related-Gut Microbiome Dysbiosis and -Metabolites in Old-Aged Mouse.
Article in Journal of microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Review
- Microplastics in early-onset carcinogenesis.Carcinogenesis · 2026Review
- Micro- and Nanoplastics Exposure Across the Lifespan: One Health Implications for Aging and Longevity.Journal of xenobiotics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microplastics, particularly polystyrene (PS), are ubiquitous environmental contaminants and concerns about their potential detrimental effects on human health are increasing. Emerging evidence suggests that microplastics may disrupt the gut microbiota, a critical ecosystem involved in regulating host metabolism, immunity, and aging processes. However, the specific effects of PS on the gut microbiota composition and its potential role in modulating aging are yet to be fully elucidated. In this study, we aimed to investigate the effects of PS exposure on gut microbiota dysbiosis and its potential role in the acceleration of aging. Gut microbiota composition was assessed using 16S rDNA sequencing, while fecal metabolites were analyzed using gas chromatography-mass spectrometry. Exposure to PS resulted in a significant reduction in the abundance of beneficial microbiota, including
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.