Evidence map›Paper›PMID 40774698›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

Lesion Absorbed Dose-Response Relationship in Patients with Metastatic Castration-Resistant Prostate Cancer Undergoing [

Milan Grkovski, Simone S Krebs, Joseph A O'Donoghue, Jonathan Kuten, Audrey Mauguen, Parnian Shobeiri, Daniel Lafontaine, Maria Thor, Finn Augensen, Josef J Fox and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. High Quantitative Accuracy Is Possible withJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  2. Dosimetry-Driven Personalization of Radiopharmaceutical Therapies: Evidence and Opportunities.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Review
  3. Overall Survival with [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  4. The predictive role of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Review
  6. PROQURE-I: a phase I study adding concurrent [European journal of nuclear medicine and molecular imaging · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Differential Clearance of [medRxiv : the preprint server for health sciences · 2025
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Milan GrkovskiDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York; grkovskm@mskcc.org schoderh@mskcc.org.
Simone S KrebsMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Joseph A O'DonoghueDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.
Jonathan KutenMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Audrey MauguenDepartment of Epidemiology-Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York; and.
Parnian ShobeiriMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Daniel LafontaineDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.
Maria ThorDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.
Finn AugensenDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.
Josef J FoxMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Neeta Pandit-TaskarMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Mark P DunphyMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Lisa BodeiMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
John L HummDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, New York.
Heiko SchöderMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; grkovskm@mskcc.org schoderh@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Interrogating the in vivo pharmacokinetics of armored CARs with radiohapten captureR37CA262557 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Simone Krebs · 2021 to 2026
$3.4M
NCI NIH HHS P30 CA008748NCI NIH HHS R37 CA262557
6 · The paper itself

Abstract

The relationship between lesion absorbed dose (AD) and response in patients with metastatic castration-resistant prostate cancer undergoing [

Indexed as

DipeptidesHeterocyclic Compounds, 1-RingLutetiumProstatic Neoplasms, Castration-ResistantRadiopharmaceuticalsAgedAged, 80 and overDose-Response Relationship, RadiationHumansMaleMiddle AgedNeoplasm MetastasisProstate-Specific AntigenRadioisotopesRadiometrySingle Photon Emission Computed Tomography Computed TomographyDipeptidesHeterocyclic Compounds, 1-RingLutetiumLutetium-177PluvictoProstate-Specific AntigenPSMA-617RadioisotopesRadiopharmaceuticals[177Lu]Lu-PSMA-617[68Ga]Ga-PSMA-11dose–response relationshipmetastatic prostate cancer

Identifiers

PMID40774698
PMCPMC12487730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.