SynthesisBone & joint open2025
Paediatric type I open tibia fractures: are antibiotics alone sufficient?
Synthesis in Bone & joint open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aims: The conventional management of the soft-tissue component of an open fracture involves emergent debridement. There is, however, evidence that questions this approach in the management of Gustilo-Anderson type I open fractures in paediatric patients. This systematic review aims to explore differences in infection rates between nonoperative management with antibiotics and operative debridement in children with type I open lower limb tibial fractures that do not require surgical fixation. Methods: A systematic review following the PRISMA guidelines was conducted. Patients aged under 18 years with Gustilo-Anderson type I open tibia fractures treated with either antibiotics alone or operative debridement were included. Polytrauma patients and those requiring operative fracture stabilization were excluded. Study bias was assessed with the ROBINS-I (Risk of Bias in Non-randomized Studies of Interventions) tool. Results: Ten retrospective studies of 123 patients with Gustilo-Anderson type I open tibial fractures were included. Nonoperative management in the emergency department with antibiotics was used in 41 patients, with two infections reported (4.87%). Operative debridement was performed in 82 patients, with two infections reported (2.33%). Conclusion: The optimum management for paediatric Gustilo-Anderson type I open tibia fractures remains unclear. There may be selected cases, with true low-energy injury without operative fixation requirements, which can be managed in the emergency department. However, there is not sufficient high-quality evidence to advocate for regular deviation from current guidelines in open tibia fractures in paediatric patients. Decision-making must take into account the energy absorbed, as this factor can be misleading within the current classification system.
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