Evidence map›Paper›PMID 40774243›Full record

ArticleThe American journal of tropical medicine and hygiene2025

Chagas and Vector-Borne Disease Exposures in an Indigenous Community in the Ecuadorian Amazon: A Retrospective Study.

Rojelio Mejia, Bin Zhan, Nestor L Uzcategui, Andrea Lopez, Philip Cooper, Natalia Romero-Sandoval

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rojelio MejiaPediatrics-Tropical Medicine, Baylor College of Medicine, Houston, Texas.
Bin ZhanPediatrics-Tropical Medicine, Baylor College of Medicine, Houston, Texas.
Nestor L UzcateguiPediatrics-Tropical Medicine, Baylor College of Medicine, Houston, Texas.
Andrea LopezSchool of Medicine, Universidad Internacional del Ecuador, Quito, Ecuador.
Philip CooperSchool of Medicine, Universidad Internacional del Ecuador, Quito, Ecuador.
Natalia Romero-SandovalSchool of Medicine, Universidad Internacional del Ecuador, Quito, Ecuador.

Funding

Serological test for detecting all geographical variances of Trypanosoma cruzi infectionR21AI171477 · NIAID · RICE UNIVERSITY · PI LILLEHOJ, PETER B · 2023 to 2024
$435k
NIAID NIH HHS R21 AI171477
6 · The paper itself

Abstract

There are limited data on vector-borne diseases from the Ecuadorian Amazon, particularly among marginalized Indigenous populations. From a survey of Shuar communities in Ecuador, we measured IgG antibodies to Trypanosoma cruzi, dengue virus, and Leishmania spp. The prevalence of IgG antibodies was 7.4% for T. cruzi, 21.3% for dengue, and 96.8% for Leishmania spp. There was an increase in the risk of dengue infections with increasing age (per year; adjusted odds ratio [adj. OR]: 1.03, 95% CI: 1.01-1.05, P = 0.001) and among females (adj. OR: 2.17, 95% CI: 1.03-4.57, P = 0.041). There was an increase in T. cruzi anti-Tc24 IgG antibody levels with greater age (Spearman r = 0.553, P = 0.05). This study showed a high prevalence or exposure to Chagas disease, dengue, and Leishmania spp. There remains an unmet need for surveillance to monitor the transmission of Chagas and other vector-borne diseases and their associated morbidity in marginalized communities in the Ecuadorian Amazon.

Indexed as

Chagas DiseaseDengueLeishmaniasisVector Borne DiseasesAdolescentAdultAgedAnimalsAntibodies, ProtozoanChildChild, PreschoolDengue VirusEcuadorFemaleHumansImmunoglobulin GAntibodies, ProtozoanImmunoglobulin G

Identifiers

PMID40774243
PMCPMC12493185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.