ArticlePoultry science2025
The effects of copper-loaded montmorillonite on intestinal morphology, microbiota, barrier function, antioxidant capacity, and gut-related gene expression in broilers.
Article in Poultry science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Palmatine-Intercalated Montmorillonite Improves Intestinal Health and Attenuates Systemic Inflammation in ETEC-Challenged Piglets.Animals : an open access journal from MDPI · 2026Article
- Effects of dietary probiotics and their combination with copper-loaded montmorillonite on growth performance, intestinal digestive function and nitrogen metabolism in yellow-feathered broilers.Poultry science · 2026Article
- Antioxidant and anti-inflammatory mechanisms of yak-derived Bacillus subtilis against Salmonella Derby-induced enteritis in mice.BMC microbiology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intestinal health is pivotal in modern poultry production, profoundly influencing growth performance and disease resistance. This study evaluated copper-loaded montmorillonite (Cu-MMT) as a novel feed additive to enhance gut health in broilers. A 21-day experiment was conducted using 270 one-day-old Arbor Acres broilers, randomly divided to three dietary treatments: a basal diet, a group supplemented with 350 mg/kg MMT, and a group supplemented with 350 mg/kg Cu-MMT. The results revealed that dietary supplementation with Cu-MMT significantly decreased the abundance of intestinal pathogens (Salmonella, Escherichia coli, and Clostridia). Concurrently, improvements in intestinal morphology were observed with Cu-MMT supplementation, characterized by elevated villus height and a higher villus height-to-crypt depth ratio. Furthermore, it reduced serum biomarkers of intestinal permeability (diamine oxidase and D-lactic acid), while upregulating the mRNA abundance of tight junction proteins (Zonula occludens-1 and occludin) and mucin-2. Furthermore, Cu-MMT outperformed MMT alone in promoting nutrient utilization, elevating digestive enzymes (amylase, lipase, trypsin) activities, and upregulating key nutrient transporters (PepT1, B
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