Evidence map›Paper›PMID 40774150›Full record

ReviewCurrent opinion in structural biology2025

Advances in native cell membrane nanoparticles system.

Weihua Qiu, Youzhong Guo

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Weihua QiuDepartment of Medicinal Chemistry, Virginia Commonwealth University, Richmond, VA 23298-0540, USA; Center for Drug Discovery, Virginia Commonwealth University, Richmond, VA 23298-0133, USA.
Youzhong GuoDepartment of Medicinal Chemistry, Virginia Commonwealth University, Richmond, VA 23298-0540, USA; Center for Drug Discovery, Virginia Commonwealth University, Richmond, VA 23298-0133, USA. Electronic address: yguo4@vcu.edu.

Funding

Proposal for an Administrative Supplement for Equipment Purchases for NIGMS Awardees NOT-GM-22-017R01GM132329 · NIGMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI GUO, YOUZHONG · 2019 to 2022
$1.9M
NIGMS NIH HHS R01 GM132329
6 · The paper itself

Abstract

The native cell membrane nanoparticles (NCMN) system utilizes membrane-active polymers specifically designed and optimized to extract and stabilize membrane proteins in the form of NCMN particlesfor biochemical and biophysical characterization. The NCMN system is a genuine and advanced detergent-free approach inspired by the membrane activity of the styrene-maleic acid copolymers (SMA), distinguishing it from the nanodisc technology, Salipro technology, and Peptidisc technology. This review introduces the current advancements in the NCMN system, including the development of NCMN polymers, the application of the NCMN system for single-particle cryo-EM analysis, and the functional characterization of membrane proteins.

Indexed as

Cell MembraneNanoparticlesCryoelectron MicroscopyHumansMaleatesMembrane ProteinsMaleatesMembrane Proteins

Identifiers

PMID40774150
PMCPMC12374768

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.