ReviewScience (New York, N.Y.)2025
Immune system influence on physiology.
Review in Science (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Gero-Immunology: The critical role of aging when defining immune phenotypes.Current opinion in biomedical engineering · 2026Article
- Article
- Metabolic Signatures Associated with COVID-19 Vaccination in Serum from Healthy Individuals.Vaccines · 2026Article
- Bifidobacterium animalis subsp. lactis and Enterococcus hirae Enhance Immunity by Modulating Gut Microbiota and Metabolic Pathways in Immunosuppressed Mice.Probiotics and antimicrobial proteins · 2026Article
- Targeting the immune-metabolic axis reverses orthodontics-induced systemic pathology.Signal transduction and targeted therapy · 2026Article
- Rediscovering eosinophil identity through tissue adaptation.Nature immunology · 2026Review
- From Viral Trafficking to Immune Surveillance: Does the Heart Harbor an Immune Landing Pad?JACC. Basic to translational science · 2026Article
- Myocardial Immune Niches in Homeostasis and Inflammation.Immunological reviews · 2026Review
- Dietary berberine supplementation regulates production performance, antioxidant capacity, and immunity of Wenchang chicken (Gallus gallus domestics).Poultry science · 2026Article
- Article
- Delphinidin Exerts Immunomodulatory Effects in Canine Neutrophils and Peripheral Blood Mononuclear Cells by Limiting Tissue Damaging Mechanisms and Regulating Cytokine Responses.Animals : an open access journal from MDPI · 2026Article
- Red Blood Cell-Derived Sealant Repair for Damaged Endothelia Jams Microvasculature in Ischemia and COVID-19 Infection.JACC. Basic to translational science · 2026Article
- The immune system as a guardian of health: micronutrient support and lifelong protection.Frontiers in nutrition · 2026Review
- The primary cilium as a compartmentalized signaling hub in tissue immunity and homeostasis.Frontiers in cell and developmental biology · 2026Review
- From microscopes to maps: enabling a new era of open and reproducible data sharing in intravital imaging.The EMBO journal · 2026Article
- Innovative Approaches to Medical Rehabilitation: Regeneration, Immune Training, Homeostasis, and Microbiome Synergy.International journal of molecular sciences · 2025Review
- On Macrophage Culture.JACC. Basic to translational science · 2025Article
- Multi-talented myeloid cells.Discovery immunology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The immune system's central function is to maintain homeostasis by guarding the organism against dangerous external and internal stressors. Immunity's operational toolbox contains diverse processes, such as phagocytosis, antigen recognition, cell killing, and secretion of cytokines and antibodies. Although immune cells interact with each other, they also communicate with cells typically associated with other organ systems, including the nervous, circulatory, metabolic, musculoskeletal, endocrine, and hematopoietic. This abundant cross-talk shows that immunity transcends defense and homeostasis: It is a network that participates in many physiological processes necessary for life. By accessing the circulation and inhabiting every tissue, leukocytes sense, interpret, and regulate biological processes. In this Review, we highlight recent studies that illustrate the often bidirectional and symbiotic relationships through which the immune system regulates physiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.