Evidence map›Paper›PMID 40773432›Full record

ArticlePloS one2025

Inequalities in disease burden and care quality of neglected tropical diseases and malaria, 1990-2021: Findings from the 2021 Global Burden of Disease Study.

Ran He, Wenhao Zhu, Shirong Hui, Meijie Yu, Haochang Li, Yihao Li, Peng Huang, Rongbin Yu

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ran HeDepartment of Epidemiology, National Vaccine Innovation Platform, Centre for Global Health, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.
Wenhao ZhuDepartment of Epidemiology, National Vaccine Innovation Platform, Centre for Global Health, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.
Shirong HuiDepartment of Epidemiology, National Vaccine Innovation Platform, Centre for Global Health, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.
Meijie YuDepartment of Epidemiology, National Vaccine Innovation Platform, Centre for Global Health, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.
Haochang LiDepartment of Epidemiology, National Vaccine Innovation Platform, Centre for Global Health, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.
Yihao LiDepartment of Epidemiology, National Vaccine Innovation Platform, Centre for Global Health, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.
Peng HuangDepartment of Epidemiology, National Vaccine Innovation Platform, Centre for Global Health, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0002-0146-921X
Rongbin YuDepartment of Epidemiology, National Vaccine Innovation Platform, Centre for Global Health, School of Public Health, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeglected Tropical Diseases (NTDs) and malaria represent significant public health threats, particularly in regions with low Socio-Demographic Index (SDI) levels. Despite global efforts to enhance prevention and control, disparities still persist. We aimed to assess the quality of care for NTDs and malaria through the quality of care index (QCI) to analyse differences in regions, genders, age groups, and to provide measures to improve the quality of care to reduce the burden of disease.

methodsUsing data from the Global Burden of Disease Study 2021 (GBD 2021), four secondary indicators were calculated using six primary indicators: incidence, mortality, prevalence, the disability-adjusted life years (DALYs), years of life lost, and years lived with disability to calculate the QCI through principal component analysis, and the gender disparity ratio was the ratio of female QCI to male QCI.

resultsGlobally, the incidence of NTDs and malaria increased, while age-standardized mortality rates (ASMRs) and DALYs declined from 1990 to 2021. In 2021, the QCI was highest in Bahrain, Qatar, and the United Arab Emirates, with scores of 91.9, 91.5, and 91.5, respectively. In contrast, Uganda, Niger, and Burkina Faso had the lowest QCIs, at 78.5, 77.1, and 75.2, respectively. QCI showed a positive correlation with a country's level of economic development, with lower quality of care observed in those under 10 and over 95 years, and largely equal quality of care received between genders.

conclusionsThis study revealed differences in the quality of care for NTDs and malaria across regions, genders, and age groups. There is an urgent need to improve care quality, particularly in low SDI areas and among young children. The study provides recommendations for enhancing the quality of care for NTDs and malaria and for developing more effective public health interventions.

Indexed as

Global Burden of DiseaseHealthcare DisparitiesMalariaNeglected DiseasesQuality of Health CareAdolescentAdultAgedChildChild, PreschoolCost of IllnessDisability-Adjusted Life YearsFemaleHumansIncidenceInfant

Identifiers

PMID40773432
PMCPMC12331120

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.