Evidence map›Paper›PMID 40773090›Full record

ArticleEndocrine2025

Factors related to lactic acidosis observed in diabetic ketoacidosis and its effect on the treatment process.

Sami Bahçebaşı, Yasin Şimşek

Abstract read
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In one paragraph

Article in Endocrine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sami BahçebaşıInternal Medicine Department, Kayseri City Hospital, Kayseri, Turkey. doktorsami@yahoo.com.ORCID 0000-0003-0909-7024
Yasin ŞimşekEndocrinology Department, Kayseri City Hospital, Kayseri, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLactic acidosis frequently accompanies diabetic ketoacidosis. The cause of lactic acidosis, its effects on treatment success, and the related factors remain unclear. This study identified the key factors contributing to lactic acidosis in diabetic ketoacidosis and their implications for treatment success. MATERIALS AND

methodsIn total, 102 patients with diabetic ketoacidosis were included in this study. The 42 patients with lactic acidosis and 60 patients with normal lactate levels were compared in terms of laboratory and clinical follow-up. Patients treated with metformin and SGLT-2 inhibitors were compared to those who did not use them in terms of ketoacidosis and lactic acidosis.

conclusionA relationship has been found between lactic acidosis observed in diabetic ketoacidosis and glucose, presence of infection, kidney function, potassium level, and duration of diabetes. Inflammation, renal dysfunction, and degree of acidosis affect the duration of intensive care and hospital stay. Lactic acidosis had no effect on the duration of the intensive care or hospital stay.

Indexed as

Acidosis, LacticDiabetes Mellitus, Type 2Diabetic KetoacidosisMetforminSodium-Glucose Transporter 2 InhibitorsAdultAgedFemaleHumansHypoglycemic AgentsLactic AcidLength of StayMaleMiddle AgedTreatment OutcomeHypoglycemic AgentsLactic AcidMetforminSodium-Glucose Transporter 2 InhibitorsDiabetic ketoacidosisInfectionLactic acidosisRenal impairment

Identifiers

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Texttitle and abstract
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.