Evidence map›Paper›PMID 40773031›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2026

Hesitancy and compulsory vaccination: are non-mandatory vaccines the victims? A study on Italian regions.

Luisa Loiacono, Riccardo Puglisi, Leonzio Rizzo, Riccardo Secomandi

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Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luisa LoiaconoDepartment of Economics and Management, University of Ferrara, Ferrara, Italy. luisa.loiacono@unife.it.ORCID http://orcid.org/0000-0002-1301-1409
Riccardo PuglisiDepartment of Social and Political Sciences, University of Pavia, Pavia, Italy.ORCID http://orcid.org/0000-0003-4658-4024
Leonzio RizzoDepartment of Economics and Management, University of Ferrara, Ferrara, Italy.ORCID http://orcid.org/0000-0001-8099-8699
Riccardo SecomandiDepartment of Economics and Management, University of Ferrara, Ferrara, Italy.ORCID http://orcid.org/0000-0002-9696-6533

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2022Università degli Studi di Ferrara FIRD 2022
6 · The paper itself

Abstract

Vaccination campaigns are estimated to prevent up to 3 million deaths worldwide annually, with their success relying on sufficient immunization coverage and adherence to programs. Recent health crises and measures like the EU Digital Covid-19 Certificate have renewed interest in the effectiveness of strategies such as recommendations, mandates, and sanctions. We analyze data on vaccinations for children aged 0-2 from Italian regions during the pre-pandemic period, 2013 to 2019. This includes both recommended and mandatory vaccines, as well as the introduction of a 2017 law mandating certain vaccinations. Our analysis shows the law increased vaccination rates for newly mandatory vaccines by up to 6%. Regional differences emerged, particularly in high-hesitancy areas where citizens tended to prioritize mandatory vaccines over recommended ones. In these regions, while coverage for mandatory vaccines improved significantly, recommended vaccines saw relatively lower attention, highlighting the need for policies that support comprehensive vaccination efforts.

Indexed as

COVID-19COVID-19 VaccinesMandatory ProgramsVaccinationVaccination HesitancyChild, PreschoolFemaleHumansImmunization ProgramsInfantInfant, NewbornItalyMaleMandatory VaccinationSARS-CoV-2Vaccination CoverageCOVID-19 VaccinesCollateral effectsHesitancyMandatory vaccinesNon-mandatory vaccinesVaccination

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.