Observational studyJournal of cataract and refractive surgery2026
Full characterization of opacifications of a specific type of hydrophilic intraocular lenses including OCT analysis.
Observational study in Journal of cataract and refractive surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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3 authors.
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Abstract
purposeTo characterize clinically and morphologically the opacification of a specific type of intraocular lenses (IOLs).
settingMiranza IOA, Madrid, Spain.
designAmbispective observational study.
methods59 eyes of 50 patients who underwent cataract surgery between 2010 and 2017 with implantation of various Lentis Mplus IOL models developed IOL opacification. The opacification was assessed through slitlamp examination and anterior segment optical coherence tomography (AS-OCT). Its impact on visual acuity (VA), far contrast sensitivity (CS), and near vision satisfaction using the 10-item Near Activity Visual Questionnaire.
resultsThe mean time to IOL opacification development was 56.4 ± 24.0 months. The most common opacification patterns were total diffuse (44.1%), peripheral plaque (33.9%), and miscellaneous (8.5%). Both uncorrected and corrected distance and near VA significantly worsened on detection of IOL opacification ( P < .001). Mean CS values for 6, 12, and 18 cycles per degree fell outside the range of normality. Fewer than 8% of patients reported extreme difficulties performing near vision tasks. OCT measurements revealed mean maximum and minimum opacification thicknesses of 72.2 ± 24.6 and 51.8 ± 21.2 μm, respectively. IOL explantation was required in 8 eyes (13.6%), with significant VA improvement after IOL exchange ( P < .001). Severe postoperative complications occurred in 3 patients after explantation.
conclusionsOpacification of Lentis Mplus IOLs typically presents with a diffuse pattern, leading to deterioration in VA and CS. This complication can be managed by exchanging the opacified IOL with a fully transparent alternative; however, the surgical procedure carries inherent risks that require careful consideration.
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