Evidence map›Paper›PMID 40772468›Full record

ArticleFuture medicinal chemistry2025

Evaluation of novel nitrophenol-triazole hybrid molecules: biological screening and computational profiling.

Sultan Onur, Mustafa Çeşme, Muhammet Köse, Ferhan Tümer

Abstract read
In one paragraph

Article in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sultan OnurDepartment of Chemistry, Faculty of Sciences, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0003-4305-9638
Mustafa ÇeşmeDepartment of Chemistry, Faculty of Sciences, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0002-2020-5965
Muhammet KöseDepartment of Chemistry, Faculty of Sciences, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0002-4597-0858
Ferhan TümerDepartment of Chemistry, Faculty of Sciences, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0003-2222-2133

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to synthesize novel nitrophenol-triazole hybrid molecules, investigate their biological activities (cholinesterase inhibition, antioxidant, and anticancer effects), and profile them using computational methods (molecular docking, ADMET). Eight new hybrid compounds were successfully synthesized, and the crystal structures of compounds

Indexed as

Antineoplastic AgentsAntioxidantsCholinesterase InhibitorsTriazolesAcetylcholinesteraseCaco-2 CellsCell ProliferationDrug Screening Assays, AntitumorHumansMolecular Docking SimulationMolecular StructureStructure-Activity RelationshipAcetylcholinesteraseAntineoplastic AgentsAntioxidantsCholinesterase InhibitorsTriazolesanticancer activityantioxidant activitycholinesterase inhibitionin silicoNitrophenolSARtriazole

Identifiers

PMID40772468
PMCPMC12506743

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.