Evidence map›Paper›PMID 40772287›Full record

ArticleACS catalysis2025

Computationally Designed Peroxygenases That Exhibit Diverse and Selective Terpene Oxyfunctionalization.

Judith Münch, Jordi Soler, Ofir Gildor-Cristal, Sarel J Fleishman, Marc Garcia-Borràs, Martin J Weissenborn

Abstract read
In one paragraph

Article in ACS catalysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Judith MünchInstitute of Chemistry, Martin Luther-University Halle-Wittenberg, Weinbergweg 22, Halle (Saale) 06120, Germany.
Jordi SolerInstitut de Qui'mica Computacional i Catàlisi and Departament de Qui'mica, Universitat de Girona, Carrer Maria Aurèlia Capmany 69, Girona 17003 Catalonia, Spain.
Ofir Gildor-CristalDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7600001, Israel.
Sarel J FleishmanDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7600001, Israel.ORCID https://orcid.org/0000-0003-3177-7560
Marc Garcia-BorràsInstitut de Qui'mica Computacional i Catàlisi and Departament de Qui'mica, Universitat de Girona, Carrer Maria Aurèlia Capmany 69, Girona 17003 Catalonia, Spain.ORCID https://orcid.org/0000-0001-9458-1114
Martin J WeissenbornInstitute of Chemistry, Martin Luther-University Halle-Wittenberg, Weinbergweg 22, Halle (Saale) 06120, Germany.ORCID https://orcid.org/0000-0002-1200-4485

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The selective oxyfunctionalization of terpenes remains a major challenge in chemical synthesis and is of significant industrial importance. This study presents a computational enzyme design approach based on an AlphaFold2 model of an unspecific peroxygenase (

Indexed as

computational chemistryenzymesFuncLiboxyfunctionalizationSaccharomyces cerevisiaeterpenesunspecific peroxygenaseyeast

Identifiers

PMID40772287
PMCPMC12322917

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.