ArticleCureus2025
Evaluating the Effect of Total Hip Arthroplasty on Bone Mineral Density in Postmenopausal Women Using an Artificial Intelligence-Assisted Osteoporosis Diagnostic System.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND AND
aimTotal hip arthroplasty (THA) alleviates pain and improves walking ability and quality of life in patients with hip osteoarthritis (OA). However, its effect on systemic bone mineral density (BMD) remains unclear. In this study, we investigated the effect of THA on systemic BMD in postmenopausal women with hip OA using an artificial intelligence (AI)-assisted osteoporosis diagnostic support system that estimates BMD solely using posteroanterior chest radiographs.
methodsThis retrospective observational study included postmenopausal Japanese women aged 50-59 years who underwent bilateral THA on separate occasions at our institution between 2007 and 2023. BMD was estimated using our AI-assisted osteoporosis diagnostic system that uses posteroanterior chest radiographs obtained approximately one month before each THA. The rate of change was compared with age-specific BMD reference values for the Japanese population.
resultsA total of 59 patients were included, with a mean age of 54.9 years and an average interval between unilateral THA of 2.1 years. Among those who underwent an initial THA at ages 50-54 years, the estimated BMD decreased by 1.52% and 0.81% annually in the lumbar spine and proximal femur, respectively. For patients who underwent an initial THA at ages 55-59 years, the estimated BMD decreased by 0.00% and 0.80% annually in the lumbar spine and proximal femur, respectively. These rates were lower than the reported rates of annual BMD decline in Japanese women aged 50-54 years (1.77%, lumbar spine; 1.27%, proximal femur) and 55-59 years (1.28%, lumbar spine; 0.88%, proximal femur).
conclusionTHA has the potential to attenuate age-related BMD decline in postmenopausal women with hip OA.
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