Evidence map›Paper›PMID 40772104›Full record

ArticleJournal of education and health promotion2025

Exploring the oxidative and inflammatory markers landscape in Buerger's disease: A comparative analysis.

Ali Asghar Asadollahi Shahir, Amir Ghaderi, Nila Navaei, Reza Zahedpasha, Somayeh Ghorbani, Hamid Reza Banafshe, Shervin-Sadat Hashemian, Abdollah Omidi

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Article in Journal of education and health promotion, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ali Asghar Asadollahi ShahirDepartment of Addiction Studies, School of Medical, Kashan University of Medical Sciences, Kashan, Iran.
Amir GhaderiDepartment of Addiction Studies, School of Medical, Kashan University of Medical Sciences, Kashan, Iran.
Nila NavaeiFaculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
Reza ZahedpashaDepartment of Radiology, School of Medicine, 5th Azar Hospital, Gorgan, Golestan, Iran, Golestan University of Medical Sciences, Gorgan, Golestan, Iran.
Somayeh GhorbaniBiostatistics, Cancer Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Hamid Reza BanafsheDepartment of Addiction Studies, School of Medical, Kashan University of Medical Sciences, Kashan, Iran.
Shervin-Sadat HashemianDepartment of Community Medicine and Health, School of Medicine, Golestan University of Medical Sciences, Golestan, Iran.
Abdollah OmidiDepartment of Clinical Psychology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBuerger's disease (BD) is characterized by inflammation and blood clotting in smaller to medium-sized blood vessels of the extremities. This study aimed to explore oxidative stress and antioxidant capacity in BD compared to healthy smokers. MATERIALS AND

methodsA case-control study was conducted, involving 10 BD patients and 10 healthy smokers as controls, with average ages of 39.4 and 53.6 years, respectively. Various serum parameters, including total cholesterol (TCh), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), very low-density lipoprotein cholesterol (VLDL-C), antioxidant status (glutathione [GSH], antioxidant capacity [TAC], malondialdehyde [MDA]), and inflammatory markers (C-reactive protein [CRP], nitric oxide [NO]), were assessed.

resultsCirculating levels of total TAC (

conclusionOverall, our study reveals notable serum distinctions between BD patients and healthy smokers. BD patients exhibit reduced antioxidant levels, increased oxidative stress, lower HDL levels, and elevated LDL, total cholesterol, and borderline high triglyceride levels.

Indexed as

AntioxidantscholesterolC-reactive proteinglutathionemalondialdehydenitric oxideoxidative stressthromboangiitis obliteranstriglycerides

Identifiers

PMID40772104
PMCPMC12327739

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.