Evidence map›Paper›PMID 40772000›Full record

ArticleCureus2025

Severe Catatonia in Early-Onset Schizophrenia Successfully Treated With Lorazepam and Aripiprazole in a 16-Year-Old Girl: A Case Report.

Ghizlane Khaloui, Salma Abchir, Amal Mabkhout, Linda Rachidi, Ghizlane Benjelloun

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ghizlane KhalouiChild and Adolescent Psychiatry Department, Abderrahim Harouchi Mother-Child Hospital, Ibn Rochd University Hospital Center, Laboratory of Clinical Neurosciences and Mental Health, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, MAR.
Salma AbchirChild and Adolescent Psychiatry Department, Abderrahim Harouchi Mother-Child Hospital, Ibn Rochd University Hospital Center, Laboratory of Clinical Neurosciences and Mental Health, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, MAR.
Amal MabkhoutChild and Adolescent Psychiatry Department, Abderrahim Harouchi Mother-Child Hospital, Ibn Rochd University Hospital Center, Laboratory of Clinical Neurosciences and Mental Health, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, MAR.
Linda RachidiChild and Adolescent Psychiatry Department, Abderrahim Harouchi Mother-Child Hospital, Ibn Rochd University Hospital Center, Laboratory of Clinical Neurosciences and Mental Health, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, MAR.
Ghizlane BenjellounChild and Adolescent Psychiatry Department, Abderrahim Harouchi Mother-Child Hospital, Ibn Rochd University Hospital Center, Laboratory of Clinical Neurosciences and Mental Health, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catatonia is a severe but often underrecognized neuropsychiatric condition in adolescents. We present the case of a 16-year-old girl with early-onset schizophrenia who developed acute catatonic symptoms during a relapse following risperidone reintroduction. The clinical presentation raised a diagnostic dilemma with neuroleptic malignant syndrome (NMS). A lorazepam trial led to partial improvement, but symptom resolution occurred only after adding low-dose aripiprazole. This case underscores the importance of early identification of catatonia in adolescents, careful differentiation from NMS, and the potential benefit of combined lorazepam and aripiprazole treatment in catatonic schizophrenia.

Indexed as

adolescentaripiprazolebenzodiazepinescatatoniaearly-onset schizophrenianeuroleptic malignant syndrome

Identifiers

PMID40772000
PMCPMC12327918

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.