Evidence map›Paper›PMID 40771981›Full record

ArticleFrontiers in neurology2025

Brain volumetric analysis of elderly patients based on hearing levels quantified using FreeSurfer.

Yun Ji Lee, Eun-Jae Lee, Chong Hyun Suh, Hye Jung Youn, Jihye Chae, Keunwoo Park, Jihoon Kweon, Joong Ho Ahn

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yun Ji LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Eun-Jae LeeDepartment of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Chong Hyun SuhDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Hye Jung YounDepartment of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jihye ChaeDepartment of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Keunwoo ParkDepartment of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jihoon KweonDepartment of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Joong Ho AhnDepartment of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study investigated the effects of hearing loss on brain volume, particularly total gray matter, the cerebellum, and the limbic system, using MRI data analyzed with FreeSurfer software. Study Design: Data was obtained from 745 individuals aged 60 or older who underwent health screenings at Asan Medical Center between March and December 2019. Participants were categorized into three groups based on their pure-tone hearing thresholds: normal hearing (<20 dB, Results: Results showed significant differences among the groups in age, sex, and health conditions such as hypertension, diabetes, and cholesterol levels ( Conclusion: The findings suggest that hearing loss in individuals over the age of 60 may contribute to the atrophy of critical brain regions, particularly the hippocampus and total gray matter. The study emphasizes the importance of addressing even mild hearing loss, as active hearing rehabilitation could potentially prevent cortical volume loss and mitigate the risk of cognitive decline.

Indexed as

FreeSurfergray matterhearing losshippocampuslimbic systemMRI

Identifiers

PMID40771981
PMCPMC12326090

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.