ArticleFrontiers in neurology2025
Identifying psychological and clinical risk factors for moderate-to-severe tinnitus in older patients with hearing loss: a multivariable prediction model.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To develop and validate a clinical prediction model for moderate-to-severe tinnitus (THI ≥ 38) in patients with hearing loss and to identify the key psychological and clinical factors associated with its risk. Methods: This retrospective single-centre study included 301 patients with hearing loss who visited Qinghai University Affiliated Hospital between August 2024 and May 2025. The cohort was randomly divided into a training set ( Results: The final multivariable model identified five independent psychological and clinical risk factors for moderate-to-severe tinnitus: older age (OR = 2.415), hypertension (OR = 2.120), poor sleep quality (OR = 2.821), anxiety (OR = 1.967), and severe hearing loss (OR = 3.452). The model demonstrated good discriminative performance, with an AUC of 0.734 in the training set and 0.760 in the validation set. Conclusion: In patients with hearing loss, psychological and clinical risk factors-including poor sleep quality, anxiety, hypertension, and severe hearing loss-were significantly associated with moderate-to-severe tinnitus. These findings underscore the need for integrated management strategies that address both psychological and clinical components of tinnitus risk.
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