Evidence map›Paper›PMID 40771956›Full record

ArticleFrontiers in veterinary science2025

Temporal changes in fecal swine microbiome primarily reflect

Antonio Diego Brandão Melo, Graziela Alves da Cunha Valini, Qinnan Yang, Marllon José Karpeggiane de Oliveira, Danilo Alves Marçal, Pedro Righetti Arnaut, Ismael França, Cleslei Alisson Silva, Nate Korth, Natasha Pavlovikj and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Antonio Diego Brandão Melo *Department of Animal Science, School of Agricultural and Veterinary Sciences, State University of São Paulo (UNESP), Jaboticabal, Brazil.
Graziela Alves da Cunha Valini *Department of Animal Science, School of Agricultural and Veterinary Sciences, State University of São Paulo (UNESP), Jaboticabal, Brazil.
Qinnan Yang *Department of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, United States.
Marllon José Karpeggiane de OliveiraDepartment of Animal Science, School of Agricultural and Veterinary Sciences, State University of São Paulo (UNESP), Jaboticabal, Brazil.
Danilo Alves MarçalDepartment of Animal Science, School of Agricultural and Veterinary Sciences, State University of São Paulo (UNESP), Jaboticabal, Brazil.
Pedro Righetti ArnautDepartment of Animal Science, School of Agricultural and Veterinary Sciences, State University of São Paulo (UNESP), Jaboticabal, Brazil.
Ismael FrançaDepartment of Animal Science, School of Agricultural and Veterinary Sciences, State University of São Paulo (UNESP), Jaboticabal, Brazil.
Cleslei Alisson SilvaDepartment of Animal Science, School of Agricultural and Veterinary Sciences, State University of São Paulo (UNESP), Jaboticabal, Brazil.
Nate KorthDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, United States.
Natasha PavlovikjHolland Computing Center, University of Nebraska-Lincoln, Lincoln, NE, United States.
Paulo Henrique Reis Furtado CamposDepartment of Animal Science, Federal University of Viçosa, Minas Gerais, Brazil.
Henrique Gastmann BrandEvonik Brazil Ltda, São Paulo, Brazil.
John Kyaw HtooEvonik Operations GmbH, Hanau, Germany.
Andrew K BensonDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, United States.
Luciano HauschildDepartment of Animal Science, School of Agricultural and Veterinary Sciences, State University of São Paulo (UNESP), Jaboticabal, Brazil.
Joao Carlos Gomes-NetoDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutrition has a significant impact on the gastrointestinal (GI) microbiome, which can influence pig metabolism, nutrient absorption, biomolecule synthesis, and bioavailability (including bile acids and short-chain fatty acids), as well as colonization resistance to GI pathogens and overall disease tolerance through immune maturation and regulation. The aim of this study was to assess the impact of functional amino acid supplementation on the fecal microbiome of pigs allocated into GOOD vs. POOR sanitary conditions (SC) over time, using 16S rRNA data. A total of 120 female growing pigs were randomly assigned in a 2 × 2 factorial arrangement (n = 30/treatment), consisting of two sanitary conditions (GOOD vs. POOR) and two diets [control (CN; 100% NRC, 2012) vs. supplemented with AA (Trp, Thr, and Met+Cys: Lys ratios increased to 20% higher than CN)]. Pigs were allocated to the GOOD SC group and were sham-inoculated, and the barn was kept clean, whereas pigs housed under POOR SC were challenged with

Indexed as

amino acidsmicrobiomeSalmonella Typhimuriumsanitary conditionswine

Identifiers

PMID40771956
PMCPMC12327394

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.