Evidence map›Paper›PMID 40771867›Full record

Trial reportJournal of multidisciplinary healthcare2025

The Effects of a Nursing Program Applying Zinc Oxide Mixed with Petroleum Jelly and Centella Asiatica Mixed with Aloe Vera on Skin Indicators Among Older Patients in Semi-Intensive Care Units: A Pilot Study.

Somphorn Chaisomsee, Samoraphop Banharak, Chakkarin Sommana, Sarunya Tuntiyasawasdikul, Supin Sim-Im, Khanisorn Ransinyo, Panita Limpawattana, Waraporn Deesui, Porntip Pimpun, Teerawat Somkamsri and 1 more

Abstract readCase ReportsClinical Trial
In one paragraph

Trial report in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Somphorn ChaisomseeNursing Department, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand.
Samoraphop BanharakDepartment of Gerontological Nursing, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand.ORCID 0000-0001-8315-0263
Chakkarin SommanaDepartment of Gerontological Nursing, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand.
Sarunya TuntiyasawasdikulCenter for Research and Development of Herbal Health Products, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Supin Sim-ImNursing Department, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand.
Khanisorn RansinyoDepartment of Gerontological Nursing, Faculty of Nursing, Khon Kaen University, Khon Kaen, Thailand.
Panita LimpawattanaDepartment of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.ORCID 0000-0003-3565-9342
Waraporn DeesuiDepartment of Internal Medicine, Namphong Hospital, Khon Kaen, Thailand.
Porntip PimpunNursing Department, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand.
Teerawat SomkamsriNursing Department, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand.
Orada SeeharachNursing Department, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Incontinence-associated dermatitis (IAD) is commonly observed in older patients admitted to intensive or semi-intensive care units, particularly those who are unable to perform daily activities independently or have restricted mobility. Once IAD occurs, it causes discomfort, pain, and loss of self-confidence, as well as increases the financial burden of treatment. This pilot study aimed to assess the feasibility of using a protective skin product to prevent and manage IAD in older patients. We applied a double-blind, randomized, block-controlled trial with a two-group pre-posttest design for this study. The study included 20 older patients admitted to a semi-intensive medical care unit. Ten participants received a nursing program that applied zinc oxide mixed with petroleum jelly, and another 10 received the same nursing program but with Centella Asiatica mixed with aloe vera. We measured the risk and severity of IAD, assessed skin moisturizer and skin pH, and analyzed data using both quantitative and qualitative methods. The results demonstrated that both tested products effectively prevented and managed IAD in older patients. They contributed to reducing the risk and severity of IAD, enhancing skin hydration, and maintaining a mildly acidic skin pH. The findings of this pilot study confirm the feasibility of using these products for older patients with incontinence. Additionally, the products were easy to apply, exhibited appropriate viscosity, created a protective barrier for the skin, reduced inflammation, and facilitated skin recovery from IAD. However, further studies with larger sample sizes and more rigorous research designs are needed to validate these findings comprehensively.

Indexed as

agedcritical caredermatitisincontinence associated dermatitisskin care

Identifiers

PMID40771867
PMCPMC12326631

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.