ArticleFrontiers in medicine2025
Prognostic implications of venous invasion in pancreatic cancer following radical surgical resection: a pathological perspective.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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6 authors.
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Abstract
Background: The assessment of resectability in borderline resectable pancreatic cancer (BRPC) primarily relies on preoperative imaging, which examines the spatial association between the tumor and adjacent vital veins, particularly the portal venous system. However, venous invasion detected via imaging is rarely confirmed by postoperative pathology. This research seeks to assess the long-term results in patients with pathologically verified venous invasion and to explore the related risk factors. Methods: This study involved 248 individuals who underwent radical pancreaticoduodenectomy (PD) from January 2011 to July 2023. Patients were classified into three categories based on preoperative imaging and postoperative pathology: no venous invasion ( Results: Patients with pathologically confirmed venous invasion exhibited significantly reduced disease-free survival (DFS) and overall survival (OS) when compared to those with either imaging-suspected or absent venous invasion ( Conclusion: Intimal venous invasion emerged as a distinct risk factor influencing postoperative survival. Radical surgical resection remains essential for attaining favorable long-term outcomes in pancreatic cancers.
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