ArticleFrontiers in medicine2025
Comparison of efficacy and safety of combined phacoemulsification, goniosynechialysis and goniotomy with trabeculectomy in advanced primary angle-closure glaucoma: a retrospective observational study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Long-Term Effects of Phacoemulsification with Goniosynechialysis in Angle-Closure Glaucoma: A 2-Year Prospective Cohort Study.Ophthalmology and therapy · 2026Article
- One-Year Outcomes of Phacoemulsification Combined with Trabecular Micro-Bypass Stent Implantation and Goniosynechialysis in Primary Angle Closure Glaucoma.Journal of clinical medicine · 2026Article
- Phacoemulsification with IOL implantation combined with goniosynechialysis and goniotomy in primary angle-closure glaucoma following failed trabeculectomy: short-term effectiveness and safety outcomes.Frontiers in medicine · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The study is a retrospective observational study. This study aimed to compare the intraocular pressure (IOP) lowering effect of phacoemulsification combined with intraocular lens implantation (PEI), Goniosynechialysis (GSL), and goniotomy (GT) vs. trabeculectomy (TRAB) in eyes with medically uncontrolled advanced primary angle-closure glaucoma (PACG) at a 12-month follow-up. Methods: Patients with medically uncontrolled advanced PACG with 360° peripheral anterior synechia (PAS) were included in this study. The patients were divided into two groups based on the surgical technique: PEI + GSL + GT and TRAB. Each patient completed a 12-month postoperative follow-up. Results: A total of 73 eyes from 71 patients were included in this study, 43 eyes of which received PEI + GSL + GT and 30 eyes of which received TRAB. At 12 months follow-up, the mean preoperative and postoperative IOP was 27.63 ± 11.38 and 16.46 ± 4.04 mmHg in the PEI + GSL + GT group ( Conclusions: PEI + GSL + GT and TRAB demonstrated comparable efficacy in lowering IOP, reducing medications, and preserving VF in medically uncontrolled advanced PACG. Moreover, PEI + GSL + GT exhibited fewer complications, avoid bleb-related complications and may be a novel minimally invasive alternative for treating advanced PACG.
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