Evidence map›Paper›PMID 40771377›Full record

ArticleGland surgery2025

Synchronous occurrence of papillary thyroid carcinoma and medullary thyroid carcinoma in the setting of Hashimoto's thyroiditis: a case report with literature review.

Yue Shi, Yu Cheng, Shuang Zhang, Lili Liu, Jianhua Gu

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In one paragraph

Article in Gland surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
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2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yue ShiThe School of Medicine, Nankai University, Tianjin, China.ORCID https://orcid.org/0009-0008-7729-3354
Yu ChengThe Department of Thyroid, Breast and Hernia Surgery, Tianjin First Central Hospital, Tianjin, China.
Shuang ZhangThe Department of Pediatrics, Tianjin Dongli Hospital, Tianjin, China.
Lili LiuThe Department of Otorhinolaryngology Head and Neck Surgery, Tianjin First Central Hospital, Tianjin, China.
Jianhua GuThe Department of Thyroid, Breast and Hernia Surgery, Tianjin First Central Hospital, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The incidence of medullary thyroid carcinoma (MTC) originating from parafollicular cells of the thyroid gland is relatively low among all thyroid cancers, and MTC combined with papillary thyroid carcinoma (PTC) is even rarer. In this article, we report a case of MTC combined with PTC on the background of Hashimoto's thyroiditis (HT) and discuss several points surrounding the diagnosis and management. Case Description: A 59-year-old woman was admitted to the hospital with the main cause of "right neck pain for 6 months and right thyroid nodules for 20 days". Ultrasound showed multiple Thyroid Imaging-Reporting and Data System (TI-RADS) grade 3 hypoechoic nodules in the right lobe, and a hypoechoic nodule in the proximal isthmus of the right lobe, with a poorly defined border and TI-RADS grade 4a. No obvious enlarged lymph nodes were seen in the anterior neck. Preoperative calcitonin (Ctn) was found to be 614.9 pg/mL (normal range, 0.00-6.40 pg/mL). Postoperative histopathologic findings returned: papillary carcinoma of the right thyroid gland, invading the peritoneum of the thyroid gland, and another more diffuse growth nodule was seen, which was consistent with medullary carcinoma of the thyroid gland; with a background of HT. The patient was successfully discharged from the hospital after surgical treatment. Conclusions: HT with PTC and MTC is an extremely rare disease. By reporting the diagnosis and treatment of this case, this article can provide experience for subsequent clinical studies.

Indexed as

artificial intelligencecase reportlymph node dissectionMedullary thyroid carcinoma (MTC)papillary thyroid carcinoma (PTC)

Identifiers

PMID40771377
PMCPMC12322752

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.