ArticleAnnals of neurosciences2025
Adjunct Bifrontal Transcranial Direct Current Stimulation in Improving Cognitive Insight and Working Memory Deficits in Schizophrenia: A Single-blind, Randomised Sham-controlled Trial.
Article in Annals of neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Cognitive deficits are an integral part of schizophrenia. This is a single-centre, single-blind randomised sham-controlled study to evaluate the effect of bilateral transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex on cognitive deficits in schizophrenia, specifically targeting improvements in cognitive insight and working memory deficits. Method: Thirty patients with schizophrenia were randomly allocated to receive 10 sessions of bilateral tDCS (anodal F3 and cathodal F4) into active and sham tDCS groups. A series of assessment tests were completed among patients having Schizophrenia, at baseline and after the 10 sessions, for instance, Beck Cognitive Insight Scale (BCIS), N-Back (0' Back) task and Trail Making Test (TMT), Scale for Assessment of Positive Symptoms (SAPS), Scale for Assessment of Negative Symptoms (SANS) and Clinical Global Impression (CGI) scale. Results: Out of a total of 30, twenty-seven participants ( Conclusion: The study suggests that the adjunctive bifrontal tDCS over DLPFC helps improve cognitive insight and working memory deficits among patients having schizophrenia.
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