Evidence map›Paper›PMID 40771105›Full record

ArticleJournal of intellectual disability research : JIDR2025

A Call for Inclusion: Children With Intellectual Disabilities in Trauma Treatment Research.

Zackary F Moore, Anna W Wright, Carine E Leslie, Allison D'Aguilar, Ananda B Amstadter, Ruth C Brown

Abstract read
In one paragraph

Article in Journal of intellectual disability research : JIDR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zackary F MooreMassey Comprehensive Cancer Center, Virginia Commonwealth University Health System, Richmond, USA.
Anna W WrightDepartment of Psychiatry, Virginia Commonwealth University, Richmond, USA.
Carine E LeslieDepartment of Psychology, Virginia Commonwealth University, Richmond, USA.
Allison D'AguilarDepartment of Psychiatry, Virginia Commonwealth University, Richmond, USA.
Ananda B AmstadterDepartment of Psychiatry, Virginia Commonwealth University, Richmond, USA.
Ruth C BrownDepartment of Psychiatry, Virginia Commonwealth University, Richmond, USA.

Funding

Wright Regional Center for Clinical and Translational ScienceUM1TR004360 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI FREDERICK Gerard MOELLER · 2023 to 2026
$16.3M
National Institutes of Health, National Center for Advancing Translational Sciences UM1TR004360NCATS NIH HHS UM1 TR004360
6 · The paper itself

Abstract

backgroundChildren with intellectual disabilities (ID) experience disparities in mental health care despite experiencing increased exposure to trauma such as physical, emotional and sexual abuse. Studies have suggested that the exclusion of people with ID from medical research may contribute to disparities in health care. It is currently unknown to what extent children with ID are excluded from trauma treatment research.

methodsAll randomised controlled trials (RCTs) (n = 62) included in the most up-to-date International Society for Traumatic Stress Studies (ISTSS) clinical care guidelines meta-analysis of posttraumatic stress disorder (PTSD) treatments were reanalysed and coded to determine whether or not children with ID or other developmental disabilities that co-occur with ID were excluded based on inclusion/exclusion criteria. Articles were double-coded by the research team. The corresponding authors of the studies were asked to complete a survey rating the likelihood that children with ID would have been eligible for the study.

resultsOf the studies, 61.3% reviewed reported exclusion criteria based on a diagnosis of intellectual disability, cognitive impairment, autism spectrum disorder, organic/neurological conditions, or other related terms (e.g., 'significant learning difficulties'). Operationalisation of exclusion criteria was sparse. Few studies reported the number of children excluded from trials based on an ID diagnosis.

conclusionsThe evidence base for the ISTSS clinical care guidelines of child PTSD treatment is not representative of children with ID. Improved documentation of inclusion/exclusion criteria, reporting of disability as a demographic characteristic, and inclusion of children with ID in PTSD treatment trials are needed to improve representation of children with ID in PTSD research.

Indexed as

Biomedical ResearchIntellectual DisabilityPatient SelectionPsychological TraumaRandomized Controlled Trials as TopicStress Disorders, Post-TraumaticChildHumanschildreninclusionintellectual disabilityposttraumatic stress disorderrandomised controlled trials

Identifiers

PMID40771105
PMCPMC12576385

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.