Evidence map›Paper›PMID 40770924›Full record

ArticleEuropean eating disorders review : the journal of the Eating Disorders Association2026

Prefrontal Cortex Recruitment to Food Stimuli Differs in Overweight/Obesity and Binge Eating Disorder.

Jennifer Svaldi, Betti Schopp, Philipp A Schroeder, Dustin Werle, Ann-Christine Ehlis

Abstract read
In one paragraph

Article in European eating disorders review : the journal of the Eating Disorders Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Prefrontal oxygenation during verbal fluency in severe obesity.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Prefrontal Cortex Recruitment to Food Stimuli Differs in Overweight/Obesity and Binge Eating Disorder.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer SvaldiDepartment of Clinical Psychology and Psychotherapy, University of Tuebingen, Tübingen Center of Mental Health (TüCMH), Tübingen, Germany.
Betti SchoppGerman Center of Mental Health (DZPG), Tübingen, Germany.
Philipp A SchroederDepartment of Clinical Psychology and Psychotherapy, University of Tuebingen, Tübingen Center of Mental Health (TüCMH), Tübingen, Germany.
Dustin WerleDepartment of Clinical Psychology and Psychotherapy, University of Tuebingen, Tübingen Center of Mental Health (TüCMH), Tübingen, Germany.
Ann-Christine EhlisGerman Center of Mental Health (DZPG), Tübingen, Germany.

Funding

Open Access Publishing Fund of University of Tübingen NASchweizerische Anorexia Nervosa Stiftung #70-16
6 · The paper itself

Abstract

backgroundAt a phenotypical level, the repeated occurrence of binge eating episodes clearly differentiates individuals with binge eating disorder (BED) from individuals with overweight but without BED. Their neural profiles during food-related inhibition, however, indicate prefrontal hypoactivation in both groups. The present study investigated differential neural activations in upper lateral (right dorsolateral prefrontal cortex [DLPFC]) and inferior (right inferior frontal gyrus [IFG]) control regions during food-related inhibition by functional near-infrared spectroscopy (fNIRS). In addition, activity in reward-related brain regions (orbitofrontal cortex [OFC]) during stimulus processing was measured.

methodIndividuals with BED (n = 32), a control group of individuals with overweight and without BED (OWC, n = 21), and a control group of individuals with normal weight and without BED (NWC; n = 31) underwent a Go/No-Go (GNG) and a stimulus degradation task during fNIRS, both with food and non-food stimuli in counterbalanced order.

resultsMost predicted outcomes were not significant. Neural recordings during GNG underscore prefrontal hypoactivation in both BED and OWC relative to NWC, however, with differential alterations: In the Food-NoGo condition, the BED group displayed hypoactivation in the IFG, while the OWC showed hypoactivation in the DLPFC.

conclusionsThe results suggest differential requirements for DLPFC and IFG recruitment during food-related inhibition in individuals with BED and overweight.

Indexed as

Binge-Eating DisorderFoodInhibition, PsychologicalObesityOverweightPrefrontal CortexAdultFemaleHumansMaleRewardSpectroscopy, Near-InfraredYoung Adultbinge eating disordercognitive controldorsal pathwayfNIRS

Identifiers

PMID40770924
PMCPMC12694698

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.