Evidence map›Paper›PMID 40770785›Full record

ArticleJournal of health, population, and nutrition2025

The association between dietary mineral intake and bone mineral density: a cross-sectional study.

Muyou Wei, Junjiang Wei, Shengsheng Huang

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Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Muyou Wei *Department of orthopedics, Yizhou District Traditional Chinese Medicine Hospital, Hechi, China.
Junjiang Wei *Department of orthopedics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Shengsheng HuangDepartment of orthopedics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China. 403432917@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMinerals are essential for maintaining bone health; however, the relationship between specific mineral intakes and bone mineral density (BMD) remains insufficiently understood. This study aims to examine the associations between the intakes of dietary minerals, including calcium (Ca), phosphorus (P), magnesium (Mg), iron (Fe), zinc (Zn), copper (Cu), sodium (Na), potassium (K), and selenium (Se), and BMD.

methodsA cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey (NHANES). Multivariate weighted generalized linear regression and smooth curve fitting were applied to evaluate the associations between dietary mineral intakes and BMD. Furthermore, subgroup analyses and interaction tests were performed to assess the consistency of these associations across different individual characteristics.

resultsA total of 11,520 representative adult participants were included in the study. Tertile-based categorical analysis revealed significant positive correlations between the intakes of Ca [β: 0.0096, 95% Confidence Interval (95% CI): (0.0001, 0.0192)], Mg [β: 0.0207, 95% CI: (0.0107, 0.0307)], Fe [β: 0.0157, 95% CI: (0.0061, 0.0253)], Zn [β: 0.0106, 95% CI: (0.0020, 0.0192)], Cu [β: 0.0088, 95% CI: (0.0000, 0.0176)], Na [β: 0.0126, 95% CI: (0.0024, 0.0228)], and Se [β: 0.0123, 95% CI: (0.0024, 0.0221)] and BMD (all P < 0.05). Smooth curve fitting and threshold effect analyses further demonstrated nonlinear relationships between mineral intakes and BMD. Subgroup analyses identified significant modulating effects of sex on the associations with Ca, Fe, and Na, as well as an interaction between diabetic status and Ca intake (all P for interaction < 0.05).

conclusionThis study elucidates the intricate relationships between dietary mineral intakes and BMD. These findings offer preliminary insights into the potential for tailored nutritional strategies in bone health management across diverse populations.

Indexed as

Bone DensityDietMineralsAdultAgedCalcium, DietaryCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysYoung AdultCalcium, DietaryMineralsBone mineral densityCross-sectional studyDietary mineral intakesNHANESOsteoporosis

Identifiers

PMID40770785
PMCPMC12330193

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.