Evidence map›Paper›PMID 40770718›Full record

ArticleBMC pulmonary medicine2025

Validation of the Distress Thermometer for detecting psychological distress in patients with stable chronic obstructive pulmonary disease: optimal cut-off score and influencing factors.

Xu Tian, Xiaoling Liu, Xiuni Gan, Maria F Jimenez-Herrera, Hongcai Shang, Yi Ren

Abstract readValidation Study
In one paragraph

Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xu TianDivision of Science & Technology and Foreign Affairs, Chongqing Traditional Chinese Medicine Hospital, Chongqing, 400020, China.
Xiaoling LiuDepartment of Nuclear Medicine, Chongqing University Cancer Hospital, Chongqing, 400030, China.
Xiuni GanDepartment of Nursing, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Maria F Jimenez-HerreraNursing Department, Universitat Rovira I Virgili, 43002, Tarragona, Spain.
Hongcai ShangDongfang Hospital, Beijing University of Chinese Medicine, No. 6 of Fangzhaung Fangxingyuan, Fengtai District, Beijing, Fengtai District, 100007, China. dzmshanghongcai@163.com.
Yi RenDepartment of Classic Traditional Chinese Medicine, Chongqing Traditional Chinese Medicine Hospital, No.6 of 7th Brach of Panxi Road, Jiangbei District, Chongqing, 400020, China. cqszyyrenyi@163.com.

Funding

Chongqing medical scientific research project (Joint project of Chongqing Health Commission and Science and Technology Bureau) 2024MSXM100
6 · The paper itself

Abstract

backgroundPatients with chronic obstructive pulmonary disease (COPD) are at high risk for psychological distress, yet validated screening tools are not routinely used in clinical practice. The Distress Thermometer (DT), originally developed for cancer patients, is a brief screening tool for detecting psychological distress. However, the optimal cut-off in COPD patients remains unclear.

aimThis study aims to validate the DT for use in stable COPD patients and to explore factors influencing psychological distress.

methodsA cross-sectional study was conducted involving 386 stable COPD patients. Data were collected using sociodemographic questionnaires, the DT, and the Hospital Anxiety and Depression scale (HADS). Receiver Operating Characteristics (ROC) analysis was employed to determine the predictive metrics of various DT cut-off scores compared to the HADS. Bivariate binary logistic regression was used to identify factors influencing psychological distress. CLINICAL TRIAL NUMBER: This cross-sectional survey study did not involve experimental interventions and therefore did not require registration in a clinical trials platform. However, the study protocol can be retrieved from https://doi.org/10.17605/OSF.IO/C3N79 .

resultsThe mean DT reported by patients was 3.77, while the mean total HADS score was 29.68. The DT score showed a high correlation with the total HADS score (r = 0.640). An optimal DT cut-off score of ≥ 5 was identified, yielding a Youden index of 0.815, with sensitivity and specificity of 97.40% and 84.14%, respectively. Using this cut-off score, the incidence of significant psychological distress was found to be 32.1%. Risk factors for psychological distress included gender, number of children, educational level, frequency of exercise, GOLD degree, and number of acute exacerbations.

conclusionsThe DT is a valid screening tool for identifying psychological distress among COPD patients. With an optimal cut-off score of ≥ 5, the DT offers high sensitivity and specificity, making it a reliable measure for clinical use. This study also highlights significant factors contributing to psychological distress, emphasizing the importance of integrating routine psychological assessments and care into the routine management of COPD to improve patient outcomes.

Indexed as

Psychological DistressPulmonary Disease, Chronic ObstructiveStress, PsychologicalAgedAnxietyCross-Sectional StudiesDepressionFemaleHumansLogistic ModelsMaleMiddle AgedROC CurveSurveys and QuestionnairesAnxietyCOPDDepressionDistress thermometerPsychological distressValidation studies

Identifiers

PMID40770718
PMCPMC12329928

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.