Evidence map›Paper›PMID 40770712›Full record

ArticleBMC surgery2025

Breaking age barriers: the efficacy of ERCP in advanced age patients.

Zhuang Li, Zhenyu Qiao, Wenfei Wang, Yanjun Sun, Dengqun Sun, Minghui Sheng

Abstract read
In one paragraph

Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhuang Li *Department of general surgery, The Chinese People's Armed Police Forces Anhui Provincial Corps Hospital, 78 Changfeng Road, Luyang District, Hefei, 230041, China.
Zhenyu Qiao *Department of general surgery, The Chinese People's Armed Police Forces Anhui Provincial Corps Hospital, 78 Changfeng Road, Luyang District, Hefei, 230041, China.
Wenfei WangDepartment of general surgery, The Chinese People's Armed Police Forces Anhui Provincial Corps Hospital, 78 Changfeng Road, Luyang District, Hefei, 230041, China.
Yanjun SunDepartment of general surgery, The Chinese People's Armed Police Forces Anhui Provincial Corps Hospital, 78 Changfeng Road, Luyang District, Hefei, 230041, China.
Dengqun SunDepartment of general surgery, The Chinese People's Armed Police Forces Anhui Provincial Corps Hospital, 78 Changfeng Road, Luyang District, Hefei, 230041, China. sundengqunsyl@126.com.
Minghui ShengDepartment of general surgery, The Chinese People's Armed Police Forces Anhui Provincial Corps Hospital, 78 Changfeng Road, Luyang District, Hefei, 230041, China. shengmh17@163.com.

Funding

Armed police Force discipline top talent fund ZG2020901Armed police Force high-level science and technology personnel fund ZG202193Armed police force science and technology innovation team independent research projects ZZKY20242101Clinical research project of Anhui University of Chinese Medicine 2024LC062Scientific research project of Anhui Provincial Health Commission AHWJ2023BAa20148the Fund of Armed police equipment research of China ZZKY20233109
6 · The paper itself

Abstract

backgroundThis study aims to evaluate the efficacy and safety of therapeutic endoscopic retrograde cholangiopancreatography (ERCP) in patients aged 75 years and older.

methodsA total of 723 patients who underwent ERCP at Anhui Provincial Corps Hospital of the Chinese People's Armed Police Force between March 2018 and April 2022 were retrospectively analyzed. This cohort included 152 patients aged ≥ 75 years (elderly group) and 571 patients aged < 75 years (control group). A 1:1 propensity score matching method was used to match the baseline characteristics of gender, stone number, and stone size between the two groups to obtain a covariate balanced sample, resulting in 152 successfully matched cases. Data on comorbidities, surgical procedures, clinical outcomes, and ERCP-related complications were collected and compared between the two groups.

resultsThe elderly cohort exhibited a significantly higher prevalence of comorbidities, including hypertension, diabetes, abnormal liver function, and cardiovascular and pulmonary diseases, when compared to the control group (p < 0.05). The primary indication for ERCP in both groups was choledocholithiasis. However, the elderly group had a notably higher incidence of a history of cholecystolithiasis and cholecystectomy (p < 0.05). The stone removal success rate was 95.39% (145/152) in both groups, and the difference between the groups was not statistically significant (P = 1). The rate of postoperative complications was 11.84% (18/152) in the elderly group and 18.42% (28/152) in the control group, with no significant difference observed (P = 0.11). Both groups demonstrated an improvement in quality of life scores following ERCP, with the elderly group showing significantly higher scores compared to the control group (p < 0.05). Long-term follow-up revealed that the recurrence of choledocholithiasis and cholangitis increased over time in the elderly group; however, no significant difference in recurrence rates was noted between the two groups (P > 0.05).

conclusionsERCP is a safe and effective therapeutic approach for elderly patients with choledocholithiasis, associated with a low incidence of complications and favorable clinical outcomes. Given its efficacy and safety profile, ERCP should be considered a treatment of choice for elderly individuals with choledocholithiasis.

Indexed as

Cholangiopancreatography, Endoscopic RetrogradeCholedocholithiasisAdultAgedAged, 80 and overAge FactorsFemaleHumansMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRetrospective StudiesTreatment OutcomeCholedocholithiasisElderlyEndoscopic retrograde cholangiopancreatographySafetySuccess rate

Identifiers

PMID40770712
PMCPMC12326853

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.