Evidence map›Paper›PMID 40770573›Full record

ArticleJournal of molecular evolution2025

Gain and Loss of Heterozygosity in the Genome of the Asexual Nematode Halicephalobus mephisto.

Ali Amini, John R Bracht

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Modified meiosis in the tardigradebioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ali AminiCenter for Data Science, American University, 4400 Massachusetts Avenue, NW, Washington, DC, 20016, USA.ORCID 0009-0008-9603-5756
John R BrachtBiology Department, American University, 4400 Massachusetts Avenue, NW, Washington, DC, 20016, USA. jbracht@american.edu.ORCID 0000-0001-8042-7685

Funding

Investigating the molecular basis of evolved stress resilience in a subterrestrial nematodeR15GM146207 · NIGMS · AMERICAN UNIVERSITY · PI BRACHT, JOHN RUSSELL · 2022 to 2023
$835k
NIGMS NIH HHS 1R15GM146207NIGMS NIH HHS R15 GM146207
6 · The paper itself

Abstract

Asexual reproduction often leads to loss of genetic diversity, but several mechanisms have evolved to maintain heterozygosity. The subterrestrial nematode, Halicephalobus mephisto, reproduces parthenogenetically, and here, we investigate how its genetic diversity

Indexed as

Genome, HelminthLoss of HeterozygosityReproduction, AsexualAnimalsGenetic VariationGenomeHeterozygoteNematodaPolymorphism, Single NucleotideAsexual evolutionExtremophile adaptationGenomicsHalicephalobus mephistoHeterozygosityMuller’s RatchetParthenogenesis

Identifiers

PMID40770573
PMCPMC12354626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.