Evidence map›Paper›PMID 40770499›Full record

ReviewAesthetic plastic surgery2025

Laser-Assisted Lipolysis: A Promising Alternative to Traditional Liposuction.

Alexander Manzano-Finol, Heliana Parra-Pelosi, Gabriel Cubillos-Valencia, Juan Urdaneta, Diego Rivera-Porras, Maricarmen Chacín, Valmore Bermúdez

Abstract readReview
In one paragraph

Review in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexander Manzano-FinolEndocrine and Metabolic Diseases Research Center, School of Medicine, Universidad del Zulia, Maracaibo, 4002, Venezuela.
Heliana Parra-PelosiEndocrine and Metabolic Diseases Research Center, School of Medicine, Universidad del Zulia, Maracaibo, 4002, Venezuela.
Gabriel Cubillos-ValenciaClínica de Obesidad y Envejecimiento, Bogotá, Colombia.
Juan UrdanetaMental Health Clinic, Insight Mental Wellness, San Antonio, Texas, 78217, USA.
Diego Rivera-PorrasDepartamento de Productividad e Innovacion, Universidad de la Costa, 080001, Barranquilla, Atlantico, Colombia.
Maricarmen ChacínFacultad de Ciencias de la Salud, Universidad Simón Bolívar, 080001, Barranquilla, Colombia.
Valmore BermúdezFacultad de Ciencias de la Salud, Universidad Simón Bolívar, 080001, Barranquilla, Colombia. valmore.bermudez@unisimon.edu.co.ORCID 0000-0003-1880-8887

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaser-Assisted Lipolysis (LAL) has emerged as a modern advancement in body contouring, offering solutions to limitations of traditional liposuction such as prolonged recovery, increased bruising, and limited skin-tightening effects. By using targeted laser energy to liquefy fat before removal, LAL minimizes tissue trauma, enhances skin retraction, and improves overall aesthetic outcomes.

objectiveTo provide a comprehensive review of the historical evolution, current technological advances, comparative methodologies, limitations, and future directions of LAL in cosmetic surgery.

methodsA narrative literature review was conducted, incorporating peer-reviewed articles, FDA-cleared devices, and clinical studies. Topics included the historical progression of LAL since its inception in the late 1990s, comparative analyses between LAL and traditional techniques, evaluation of laser wavelengths (e.g., 1064, 1320, 1444, and 1470 nm), and examination of innovations such as dual-wavelength systems, robotic-assisted delivery, AI-guided planning, and radiofrequency-assisted methods.

resultsLAL shows clinical advantages including faster recovery times, reduced postoperative pain, and improved skin tightening, especially in small to moderate fat reduction areas. Dual- and multi-wavelength lasers, pulse modulation, and fiber-optic temperature sensing improve precision and safety. Comparative studies show LAL achieves better outcomes than traditional liposuction in certain contexts, particularly for skin appearance and submental fat reduction. However, variability in laser parameters, higher procedural costs, and limitations in autologous fat reuse remain concerns. Research also highlights promising applications of LAL in large-volume fat removal and potential bariatric contexts.

conclusionLAL has evolved into a valuable technique in modern aesthetic surgery. While not a replacement for traditional liposuction in all cases, it offers meaningful benefits as a stand-alone or adjunct procedure. Continued innovations, such as nanotechnology, biodegradable fibers, and AI-assisted planning, may further enhance its effectiveness, precision, and personalization in future body contouring practices. Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Indexed as

Body ContouringLaser TherapyLipectomyEstheticsFemaleHumansMaleTreatment OutcomeFat removalLaser-assisted lipolysisMinimally invasive laser treatmentsMulti-wavelength systemTraditional liposuction

Identifiers

PMID40770499
PMCPMC12594724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.