ArticleCurrent medical imaging2025
Clinical Outcomes of Patients with Adrenal Incidentaloma - Hypertension being a Continuous Risk Factor for the Presence of Comorbidity: A Single Center's Eight-year Experience.
Article in Current medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- The Relationship Between Bone Health Status of Post-Menopausal Women with Non-Functional Adrenal Tumours/Mild Autonomous Cortisol Secretion and Their Baseline Morning Adrenocorticotropic Level.Diagnostics (Basel, Switzerland) · 2026Article
- A longitudinal study of dual-energy X-ray absorptiometry status in menopausal women with adrenal tumors.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
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6 authors.
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Abstract
backgroundAdrenal incidentalomas have increased over the past years. Although there are a lot of studies related to the frequency of adrenal masses and comorbidities, whether patients with functional or nonfunctional adrenal masses have higher risk is still a controversial issue.
methodsA total of 464 patients (female/male: 309/155) with adrenal incidentalomas were evaluated and followed up for 8 years. The patients were divided into 5 subgroups, including Autonomous Cortisol Secretion (ACS), Cushing Syndrome (CS), Pheochromocytoma (Pheo), Non-functional Adrenal Incidentalomas (NFAI), and Primary Aldosteronism (PA).
resultsWhile 336 (72.4%) of the patients had NFAI, the others suffered from ACS (10.8%), CS (4.3%), Pheo (4.1%), and PA (8.4%), respectively. When comparing biochemical and demographical data, BMI (p=0.77), Hba1c (p=0.495), FPG (p=0.28), LDL (p=0.66), and HDL (p=0.521) were similar among the patients with functional and nonfunctional adrenal masses. The most common comorbidities were hypertension (n=259, 55.8%), diabetes mellitus (n=158, 34.1%), and dyslipidemia (33.4%), respectively. While 84 (32.4%) patients with hypertension had functional adrenal masses, the others (n=175, 67.6%) had non-functional adrenal incidentalomas. In subgroup analyses, hypertension was more common in patients with PA (87.2% vs. 72%, p=0.001) and ACS. In multivariable regression analyses, hypertension (p<0.001), cortisol (p=0.003), and aldosterone (p=0.04) levels were significantly correlated with functionality.
conclusionHypertension was the most common comorbidity in patients with adrenal adenomas, especially in functional adrenal adenomas related to serum cortisol and aldosterone levels.
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