Evidence map›Paper›PMID 40770429›Full record

ReviewCardiovascular and interventional radiology2026

Retrospective Clinical Studies in Interventional Oncology: Relevance and Challenges.

Johannes Uhlig, Thomas Kroencke, Hyun S Kim

Abstract readReview
In one paragraph

Review in Cardiovascular and interventional radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Clinical Trials in Interventional Oncology: A Field Growing Up Fast.Cardiovascular and interventional radiology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Johannes UhligDepartment of Clinical and Interventional Radiology, University Medical Center Goettingen, Goettingen, Germany. johannes.uhlig@med.uni-goettingen.de.ORCID http://orcid.org/0000-0003-3557-3194
Thomas KroenckeDepartment of Diagnostic and Interventional Radiology, University Hospital Augsburg, Augsburg, Germany.
Hyun S KimDivision of Vascular and Interventional Radiology, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retrospective clinical studies are critical in interventional oncology (IO), offering insights by analyzing existing data. They are cost-effective, time-efficient, and invaluable for exploring real-world treatment trends, long-term effects, and rare diseases. Retrospective studies provide critical support for hypothesis generation, post-marketing surveillance, and addressing ethically or logistically challenging questions unsuitable for prospective or randomized controlled trials (RCTs). To maximize their utility, retrospective studies must ensure robust data quality, clear objectives, advanced statistical methods, and transparency. Despite challenges like biases and limited causal inference, their ability to complement RCTs and other types of prospective trials help to close crucial gaps in evidence generation, which makes them indispensable for research in the rapidly evolving field of interventional oncology.

Indexed as

Medical OncologyNeoplasmsHumansResearch DesignRetrospective StudiesCancer research methodsEvidence-based oncologyInterventional oncologyRetrospective cancer studies

Identifiers

PMID40770429
PMCPMC13156129

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.