ArticleVirology journal2025
Characterization of an unusual tobacco rattle virus isolate and a novel phenuivirid in the Jerusalem sage.
Article in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Jerusalem sage (Phlomis fruticosa) is a popular ornamental in Europe. In 2022, typical virus-like symptoms consisting of chlorotic rings and irregular patches were identified on leaves of this plant species in Lausanne, Switzerland.
methodsHigh-throughput sequencing was used on symptomatic samples, which was followed by transmission electron microscopy, sap inoculations of indicator species, and RT-PCR analyses.
resultsTwo RNA viruses were identified. The first one represents a novel isolate of tobacco rattle virus (TRV) named “Phlo”. Its presence was confirmed in symptomatic plants but not in asymptomatic ones. Phlo is distinguished by its exceptionally long RNA2 that harbours a peculiar genetic make-up, which could be associated with host-specific systemic infection ability. The second virus, detected both in symptomatic and asymptomatic sages, is a novel member of the family Phenuiviridae named “phlomis phenuivirus 1” (PPV1). PPV1 exhibits a “cogu-like” architecture with a bi-segmented, ambisense RNA genome encoding a replicase, nucleocapsid, and putative movement protein. PPV1 is related to muscari virus A, and together they likely constitute a new genus for which the name “Maladivirus” is proposed.
conclusionsTRV Phlo is most likely responsible for the symptoms observed on the Jerusalem sages. PPV1 may be latent on this species, although there are still uncertainties regarding its host.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.