ReviewNutrition & metabolism2025
Cornelian cherry, cardiometabolic health, and dietary intake: a GRADE-assessed systematic review and meta-analysis.
Review in Nutrition & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Beyond Antioxidants: The Microbial Metabolic Landscape of Anthocyanins and Their Downstream Health Implications.Nutrients · 2026Review
- Untargeted UHPLC-HRMS Metabolomic Profiling ofAntioxidants (Basel, Switzerland) · 2025Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven the essential role of cardiometabolic risk factors in the global burden of chronic diseases, this study aimed to assess the potential of cornelian cherry(Cornus mas L.) in improving anthropometric parameters, lipid profile, glycemic indices, liver enzyme levels, and dietary intake of energy and macronutrients.
methodsWe conducted a systematic search of PubMed, Scopus, Web of Science, and the Cochrane Library for eligible randomized controlled trials(RCTs) published up to May 2025, with no restrictions on language or publication date. The weighted mean difference(WMD) and 95% confidence interval(95%CI) for each outcome were determined using a random-effects model. The certainty of the assessments was further examined using the GRADE assessment.
resultsSeven RCTs were included in the final analysis. Pooled effect size showed that Cornus mas L(CM) intake significantly reduced body weight (MD:-0.57 Kg,95%CI:-1.03,-0.12;P = 0.013), body mass index(MD:-0.38 kg/m2,95%CI:-0.52,-0.23;P = 0.001), fat mass (MD:-0.97%,95%CI:-1.53,-0.41;P = 0.001), waist circumference (MD:-1.36 cm,95%CI:-1.80,-0.92;P = 0.001), and hip circumference(MD:-0.95 cm,95%CI:-1.55,-0.36;P = 0.002), triglycerides(MD:-30.6 mg/dl,95%CI:-61.0,-0.14;P = 0.049), fasting blood sugar (FBS) (MD:-5.72 mg/dl,95%CI:-11.25,-0.20;P = 0.042), and hemoglobin A1c(HbA1c)(MD:-0.28,95%CI:-0.35,-0.20;P = 0.001). Additionally, CM increased high-density lipoprotein-cholesterol levels(MD:2.03 mg/dl,95%CI:0.82,3.25;P = 0.001). However, we observed no significant effects of CM intake on total cholesterol levels, low-density lipoprotein-cholesterol, insulin, aspartate aminotransferase, and alanine aminotransferase.
conclusionsThe findings of our meta-analysis indicate that consuming CM can positively affect CMR factors. These benefits include improved anthropometric parameters, including body weight, body mass index, fat mass, waist circumference, and hip circumference, a reduction in glycemic parameters such as FBS and HbA1c, and an improvement in lipid profile. However, the study did not reveal any significant impact of CM consumption on insulin, total cholesterol, and liver enzyme levels.
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