Evidence map›Paper›PMID 40770298›Full record

Observational studyBMC public health2025

Associations of migrant and refugee status with physical comorbidity and mortality among young adults with incident non-affective psychotic disorders.

Alexis E Cullen, Christopher J de Montgomery, Emma Pettersson, Aemal Akhtar, Marie Norredam, Heidi Taipale, Ellenor Mittendorfer-Rutz

Abstract readObservational Study
In one paragraph

Observational study in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Alexis E CullenDepartment of Clinical Neuroscience, Division of Insurance Medicine, Karolinska Institutet, Berzelius vag 3, Stockholm, 171 77, Sweden. alexis.cullen@ki.se.
Christopher J de MontgomeryDepartment of Clinical Neuroscience, Division of Insurance Medicine, Karolinska Institutet, Berzelius vag 3, Stockholm, 171 77, Sweden.
Emma PetterssonDepartment of Clinical Neuroscience, Division of Insurance Medicine, Karolinska Institutet, Berzelius vag 3, Stockholm, 171 77, Sweden.
Aemal AkhtarDepartment of Clinical Neuroscience, Division of Insurance Medicine, Karolinska Institutet, Berzelius vag 3, Stockholm, 171 77, Sweden.
Marie NorredamDepartment of Public Health, Danish Research Centre for Migration, Ethnicity and Health (MESU), University of Copenhagen, Copenhagen, Denmark.
Heidi TaipaleDepartment of Clinical Neuroscience, Division of Insurance Medicine, Karolinska Institutet, Berzelius vag 3, Stockholm, 171 77, Sweden.
Ellenor Mittendorfer-RutzDepartment of Clinical Neuroscience, Division of Insurance Medicine, Karolinska Institutet, Berzelius vag 3, Stockholm, 171 77, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhilst a 'healthy migrant effect' has been reported for some migrant groups, it is unclear whether this generalises to individuals with non-affective psychotic disorders (NAPDs), a population characterised by increased risk of physical morbidity and mortality. We aimed to compare the risk of developing physical conditions, all-cause mortality, and suicide among Swedish-born, non-refugee migrant, and refugee individuals with incident NAPDs.

methodIn this register-based cohort study, nationwide registers were used to identify individuals aged 18-35 years who received their first diagnosis of NAPD in inpatient/specialist outpatient care between 1 January 2006 and 31 December 2013. Individuals were followed from the date of cohort entry until 31 December 2018 or death/emigration. Cox proportional hazards models (yielding hazard ratios, HRs and 95% confidence intervals, CI), incorporating inverse-probability weights to account for covariate differences across population groups, were used to compare the risk of specific physical disorders, all-cause mortality, and suicide in refugees and non-refugee migrants to their Swedish-born peers.

resultsWe identified 7,733 individuals (median age 26, IQR 22-30 years; 63.6% male) with incident NAPDs. Compared to their Swedish-born peers, the risk of developing type 2 diabetes was significantly increased among refugees (HR = 2.48, 95% CI = 1.56-3.95) and non-refugee migrants (HR = 1.66, 95% CI = 1.01-2.71) with NAPDs, refugees were also at higher risk of infectious diseases (HR = 1.30, 95% CI = 1.09-1.55). No significant differences in cardiovascular and respiratory diseases were observed. In contrast, refugees with NAPDs had lower risk of all-cause mortality (HR = 0.59, 95% CI = 0.39 - 0.91) and deaths due to suicide (HR = 0.57, 95% CI = 0.34 - 0.96) compared to Swedish-born individuals with NAPDs.

conclusionAmong those with NAPDs, migrants (particularly refugees) are at greater risk of developing diabetes and infectious diseases. Given the global increase in refugee populations, our findings have important implications for healthcare providers and suggest that these vulnerable individuals may require closer monitoring of physical health.

Indexed as

Diabetes Mellitus, Type 2InfectionsPsychotic DisordersRefugeesTransients and MigrantsAdolescentAdultComorbidityFemaleHumansIncidenceMaleProportional Hazards ModelsRegistriesSuicideSwedenHealth inequalitiesImmigrationMultimorbiditySchizophreniaSomatic disorders

Identifiers

PMID40770298
PMCPMC12326835

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.