Articlenpj aging2025
Age-related alterations in alpha and beta oscillations support preservation of semantic processing in healthy aging.
Article in npj aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- High-resolution MRI evidence for age- and sex-related changes in hippocampal subfield volume during healthy aging.GeroScience · 2026Article
- Neurovascular decoupling and compensatory network recruitment during speech perception in aging: evidence from EEG-fNIRS.GeroScience · 2026Article
- Facial expression processing is modulated by face gender and anxiety levels in developing youth.Developmental cognitive neuroscience · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Funding
Abstract
Semantic processing remains relatively preserved during healthy aging, but the mechanisms are poorly understood. Herein, we use dynamic functional mapping based on magnetoencephalography to examine the neural oscillations serving semantic processing across the adult lifespan (N = 154; 21-87 years). Task-related oscillatory dynamics were imaged using a beamformer and whole-brain linear mixed-effects (LME) models were calculated with age and task condition (semantically-related or -unrelated) as factors. LMEs revealed significant age-by-condition interactions on alpha and beta activity in multiple regions, which generally reflected stronger responses with increasing age and/or in the semantically-related condition across regions (p values < 0.005, corrected). Follow-up mediation analyses of these interaction clusters indicated that left perisylvian alpha responses suppressed the effect of age on verbal fluency (p = 0.014), with larger conditional differences in this region supporting preserved fluency with increasing age. Our findings provide novel insight on age-related neurophysiological adaptations that support preservation of semantic processing.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.