ArticleSocial psychiatry and psychiatric epidemiology2026
Effects of sarcopenic obesity on depressive symptoms and their trajectories: findings from the CHARLS 2011-2020.
Article in Social psychiatry and psychiatric epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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8 authors.
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Abstract
purposeSarcopenia and obesity are recognized factors associated with the onset of depression. Our study aims to clarify the specific impact of sarcopenic obesity on depression development and the longitudinal trajectories of depressive symptoms.
methodsData from the 2011-2020 China Health and Retirement Longitudinal Study (CHARLS) were utilized, including 8532 participants aged ≥ 45 years. Cox proportional hazards regression assessed the effect of sarcopenic obesity on the incidence of depression. Restricted cubic spline (RCS) regression explored the relationship between components of sarcopenic obesity (waist circumference, BMI, handgrip strength, and appendicular skeletal muscle mass index (ASM/Ht
resultsSarcopenic non-obesity (HR = 1.15; 95% CI: 1.03-1.28) and sarcopenic obesity (HR = 1.28; 95% CI: 1.04-1.58) were associated with increased depression risk. RCS analysis revealed a significant dose-response relationship between components of sarcopenic obesity (waist circumference, BMI, handgrip strength, and ASM/Ht
conclusionsSarcopenic obesity is associated with an increased risk of depression and may affect the progression of depressive symptoms. Improving muscle mass and strength and maintaining moderate abdominal fat in middle-aged and older adults could help prevent depression.
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