SynthesisPediatric research2026
Role of functional echocardiography in neonatal shock: a systematic review and meta-analysis.
Synthesis in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- A Comprehensive Review of the Approach to Ultrasonography in Neonatal Shock: The Partnership Between Targeted Neonatal Echocardiography and Point-of-Care Ultrasound.Children (Basel, Switzerland) · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPoint of care functional echocardiography is an emerging tool in neonatology to assess hemodynamic dysfunction and its timely management.
methodsFollowing PRISMA guidelines, we searched PubMed, EMBASE, CINAHL, Medline, and Web of Sciences databases till December 2024. We selected 2680 text articles of which 21 studies qualified for full-text review and finally, eight studies were included in the systematic review.
resultsMeta-analysis using REM (Random effects model) showed no significant difference in the primary outcome of Inferior Vena Cava Collapsibility Index (IVC-CI) between shock versus controls [SMD = -0.99 (95% CI: -2.89, 0.91), P = 0.31, I
conclusionsThis review reinforces the clinical utility of echocardiographic parameters in diagnosing and monitoring neonatal shock and underscores the need for conducting multicentre, prospective studies to validate dynamic changes in echocardiographic parameters before and after treatment of shock. IMPACT: Our study highlights role of functional echocardiography as an adjunct to clinical and biochemical markers of shock in neonates providing more comprehensive understanding of cardiac function. No significant difference in the Inferior Vena Cava Collapsibility Index values was seen in neonates with shock. However, Shortening Fraction, Left Ventricle Velocity Time Integral, Right Ventricle Velocity Time Integral, and Ejection Fraction were significantly decreased in this group. Impact of this study lies in its potential to increase researchers' awareness of need to conduct multicentre, prospective studies to validate dynamic changes in echocardiographic parameters before and after treatment of shock.
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Registered trials
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