Evidence map›Paper›PMID 40769902›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Histopathological Examination of Clustering Microspheres and Podocyte Infolding in the Glomerular Basement Membrane Using Low-vacuum Scanning Electron Microscopy.

Shingo Nakayama, Takuo Hirose, Hideaki Hashimoto, Akari Endo, Ikuko Oba-Yabana, Tomoyoshi Kimura, Wako Yumura, Takefumi Mori

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shingo NakayamaDivision of Nephrology and Hypertension, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Japan.
Takuo HiroseDivision of Nephrology and Hypertension, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Japan.
Hideaki HashimotoDivision of Nephrology and Hypertension, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Japan.
Akari EndoDivision of Nephrology, Tohoku Medical and Pharmaceutical University Wakabayashi Hospital, Japan.
Ikuko Oba-YabanaDivision of Nephrology and Hypertension, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Japan.
Tomoyoshi KimuraDivision of Nephrology, Tohoku Medical and Pharmaceutical University Wakabayashi Hospital, Japan.
Wako YumuraDivision of Nephrology and Hypertension, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Japan.
Takefumi MoriDivision of Nephrology and Hypertension, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Podocyte infolding (PI) in a thickened glomerular basement membrane (GBM) is a rare pathological finding in electron microscopy (EM). We histopathologically evaluated a 57-year-old Japanese male patient with clustering microspheres and PI in the GBM. EM showed clustering microspheres in irregularly thickened GBM and PI into the GBM. Endothelial cells also invaded the GBM on EM. Low-vacuum scanning EM revealed numerous openings or holes in the GBM. Careful examination by EM is needed to identify further cases of clustering microspheres and PI. It is also important to explore these cases using new approaches such as low-vacuum scanning EM.

Indexed as

Glomerular Basement MembraneMicroscopy, Electron, ScanningMicrospheresPodocytesHumansMaleMiddle Agedclustering microsphereselectron microscopykidney biopsylow-vacuum scanning electron microscopypodocyte infolding

Identifiers

PMID40769902
PMCPMC13019003

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.