Evidence map›Paper›PMID 40769901›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Atypical Presentation of Intravascular Large B-cell Lymphoma After Treatment for Antineutrophil Cytoplasmic Antibody-associated Vasculitis.

Seigi Oshima, Mitsuhiro Shimada, Hiro Ikeda, Shungo Mochizuki, Yui Fukuda, Miho Miyauchi, Tomomi Endo, Gen Honjo, Tatsuo Tsukamoto, Toshiyuki Kitano

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Seigi OshimaDepartment of Hematology, Medical Research Institute Kitano Hospital, PIIF Tazuke-Kofukai, Japan.
Mitsuhiro ShimadaDepartment of Hematology, Medical Research Institute Kitano Hospital, PIIF Tazuke-Kofukai, Japan.
Hiro IkedaDepartment of Hematology, Medical Research Institute Kitano Hospital, PIIF Tazuke-Kofukai, Japan.
Shungo MochizukiDepartment of Nephrology and Dialysis, Medical Research Institute Kitano Hospital, PIIF Tazuke-Kofukai, Japan.
Yui FukudaDepartment of Nephrology and Dialysis, Medical Research Institute Kitano Hospital, PIIF Tazuke-Kofukai, Japan.
Miho MiyauchiDepartment of Nephrology and Dialysis, Medical Research Institute Kitano Hospital, PIIF Tazuke-Kofukai, Japan.
Tomomi EndoDepartment of Nephrology and Dialysis, Medical Research Institute Kitano Hospital, PIIF Tazuke-Kofukai, Japan.
Gen HonjoDepartment of Pathology, Medical Research Institute Kitano Hospital, PIIF Tazuke-Kofukai, Japan.
Tatsuo TsukamotoDepartment of Nephrology and Dialysis, Medical Research Institute Kitano Hospital, PIIF Tazuke-Kofukai, Japan.
Toshiyuki KitanoDepartment of Hematology, Medical Research Institute Kitano Hospital, PIIF Tazuke-Kofukai, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a rare case of intravascular large B-cell lymphoma (IVLBL) that developed during treatment of antineutrophil cytoplasmic antibody-associated vasculitis (AAV). A 77-year-old woman presented with elevated lactate dehydrogenase levels and pancytopenia. The patient did not have a fever. Elevation of soluble IL-2 receptors without lymphadenopathy raised suspicion of IVLBL. The diagnosis was confirmed by a random skin biopsy, but the patient was refractory to therapy and died. Our case highlights potential complications of AAV with IVLBL. Patients with IVLBL, particularly after receiving immunosuppressive agents, may not exhibit a fever and may have a poor prognosis owing to acquired resistance to chemotherapy.

Indexed as

Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisLymphoma, Large B-Cell, DiffuseVascular NeoplasmsAgedFatal OutcomeFemaleHumansImmunosuppressive AgentsReceptors, Interleukin-2Immunosuppressive AgentsReceptors, Interleukin-2ANCA-associated vasculitisautoimmune diseaseintravascular large B-cell lymphomapancytopenia

Identifiers

PMID40769901
PMCPMC13019023

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.